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Vol 15, No 3-4 (2009)
Research paper
Published online: 2010-01-27

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Urine haemosiderin: a marker of chronic venous insufficiency

Radosław Piotrowicz, Tomasz Grzela, Arkadiusz Jawień, Magdalena Kuligowska-Prusińska
Acta Angiologica 2009;15(3-4):101-107.


Background. Chronic venous insufficiency (CVI) is one of the most significant health problems of developed countries. Tissue deposits of iron play an important role in the pathogenesis of trophic skin changes. The purpose of the study was to test the correlation of clinical severity of venous insufficiency with urine excretion of hemosiderin.
Material and methods. Urine sediments were stained for hemosiderin granules with Perl reagent. The urine samples of 76 persons representing various categories of venous insufficiency were evaluated.
Results. There was no correlation between clinical category of venous insufficiency and number of hemosiderin granules noticed in urine.
Conclusions. Thus, hemosiderinuria cannot be a marker of severity of venous disturbances.

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