open access

Vol 15, No 3-4 (2009)
Original papers
Published online: 2010-01-27
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Urine haemosiderin: a marker of chronic venous insufficiency

Radosław Piotrowicz, Tomasz Grzela, Arkadiusz Jawień, Magdalena Kuligowska-Prusińska
Acta Angiologica 2009;15(3-4):101-107.

open access

Vol 15, No 3-4 (2009)
Original papers
Published online: 2010-01-27

Abstract

Background. Chronic venous insufficiency (CVI) is one of the most significant health problems of developed countries. Tissue deposits of iron play an important role in the pathogenesis of trophic skin changes. The purpose of the study was to test the correlation of clinical severity of venous insufficiency with urine excretion of hemosiderin.
Material and methods. Urine sediments were stained for hemosiderin granules with Perl reagent. The urine samples of 76 persons representing various categories of venous insufficiency were evaluated.
Results. There was no correlation between clinical category of venous insufficiency and number of hemosiderin granules noticed in urine.
Conclusions. Thus, hemosiderinuria cannot be a marker of severity of venous disturbances.

Abstract

Background. Chronic venous insufficiency (CVI) is one of the most significant health problems of developed countries. Tissue deposits of iron play an important role in the pathogenesis of trophic skin changes. The purpose of the study was to test the correlation of clinical severity of venous insufficiency with urine excretion of hemosiderin.
Material and methods. Urine sediments were stained for hemosiderin granules with Perl reagent. The urine samples of 76 persons representing various categories of venous insufficiency were evaluated.
Results. There was no correlation between clinical category of venous insufficiency and number of hemosiderin granules noticed in urine.
Conclusions. Thus, hemosiderinuria cannot be a marker of severity of venous disturbances.
Get Citation

Keywords

hemosiderin; chronic venous insufficiency; chronic venous disturbances; marker of venous disease; Perl reagent

About this article
Title

Urine haemosiderin: a marker of chronic venous insufficiency

Journal

Acta Angiologica

Issue

Vol 15, No 3-4 (2009)

Pages

101-107

Published online

2010-01-27

Bibliographic record

Acta Angiologica 2009;15(3-4):101-107.

Keywords

hemosiderin
chronic venous insufficiency
chronic venous disturbances
marker of venous disease
Perl reagent

Authors

Radosław Piotrowicz
Tomasz Grzela
Arkadiusz Jawień
Magdalena Kuligowska-Prusińska

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