Żylna choroba zakrzepowo-zatorowa — wytyczne profilaktyki, diagnostyki i terapii Konsensus Polski 2017

Abstract

Polish Consensus Statement 2017 (PCS 2017) comprises updated recommendations on prophylaxis, diagnostic approach and treatment of venous thromboembolism (VTE). For VTE and no cancer, as long-term anticoagulant therapy, the authors of PCS 2017 recommend apixaban, edoxaban, rivaroxaban and dabigatran over vitamin K antagonists (VKA). For VTE and cancer, the authors of PCS 2017 recommend low molecular weight heparins (LMWH) over VKA, apixaban, edoxaban, rivaroxaban and dabigatran. For extended prophylaxis of deep venous thrombosis (DVT), PCS 2017 recommends apixaban, edoxaban, rivaroxaban, dabigatran, VKA and sulodexide. For extended prophylaxis of pulmonary embolism (PE) PCS 2017 recommends apixaban, edoxaban, rivaroxaban, dabigatran and VKA. In extended prophylaxis, for patients with idiopathic DVT and high risk of bleeding complications, the authors of PCS 2017 recommend DO NOT stop anticoagulation and use of sulodexide. In extended prophylaxis, for patients with idiopathic PE and high risk of bleeding, the authors of PCS 2017 recommend DO NOT stop anticoagulation and suggests treatment with apixaban, edoxaban, rivaroxaban and dabigatran in reduced doses — adjusted to the risk of bleeding. For VTE treated with anticoagulants, PCS 2017 recommends against insertion of vena cava filters. For patients with DVT, PCS 2017 suggests USING compression stockings routinely to prevent post thrombotic syndrome. For sub-segmental PE and no proximal DVT, PCS suggests clinical surveillance over anticoagulation with a low risk of recurrent VTE, and anticoagulation over clinical surveillance with a high risk. Polish Consensus Statement 2017 suggests thrombolytic therapy for PE with hypotension and systemic therapy over catheter directed thrombolysis. For recurrent VTE on a non-LMWH anticoagulant, PCS suggests LMWH, and for recurrent DVT and/or PE on LMWH PCS 2017 suggests increasing the LMWH dose.