open access

Vol 18, No 2 (2012)
Original papers
Published online: 2012-09-10

Therapeutic problems in patient with hereditary hemorrhagic teleangiectasia and venous thromboembolic disease

Rafał Małecki, Weronika Rydel, Anna Stępień, Agnieszka Orchowska-Jędrzejewska, Andrzej Dołyk, Rajmund Adamiec
Acta Angiologica 2012;18(2):79-85.

open access

Vol 18, No 2 (2012)
Original papers
Published online: 2012-09-10

Abstract

Rendu-Osler-Weber disease (hereditary hemorrhagic teleangiectasia, HHT) is a dominant disorder that leads
to multiorgan vascular dysplasia, involving teleangiectasias and arteriovenous malformations of the skin, the
nose, lungs, the alimentary tract and the central nervous system. Thromboembolic incidents in patients with
HHT occur rarely, however present serious therapeutic challenge. We present a case of 57-year old male
patient with HHT and lower extremity deep vein thrombosis, complicated with pulmonary embolism in whom
administration of antithrombotic drugs in therapeutic dose resulted in uncontrollable epistaxis. Eventually,
embolization of bleeding vessels enabled the therapy with accurate dosage of anticoagulant drug.

Keywords

hemorrhagic teleangiectasia, Rendu-Osler-Weber disease, pulmonary embolism, deep vein thrombosis

About this article
Title

Therapeutic problems in patient with hereditary hemorrhagic teleangiectasia and venous thromboembolic disease

Journal

Acta Angiologica

Issue

Vol 18, No 2 (2012)

Pages

79-85

Published online

2012-09-10

Bibliographic record

Acta Angiologica 2012;18(2):79-85.

Keywords

hemorrhagic teleangiectasia
Rendu-Osler-Weber disease
pulmonary embolism
deep vein thrombosis

Authors

Rafał Małecki
Weronika Rydel
Anna Stępień
Agnieszka Orchowska-Jędrzejewska
Andrzej Dołyk
Rajmund Adamiec

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