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Vol 18, No 2 (2012)
Review paper
Published online: 2012-09-10

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Direct thrombolysis in the treatment of the acute central retinal artery occlusion

Małgorzata Czechowska, Zdzisława Kornacewicz-Jach, Andrzej Modrzejewski, Wojciech Lubiński, Jarosław Gorący, Maciej Lewandowski
Acta Angiologica 2012;18(2):51-58.


Central retinal artery occlusion (CRAO) is an acute disease which often leads to the blindness. Current ways
of treatment still are not very sufficient. The development of the endovascular techniques as well as their
good results are the reason for numerous attempts of the intraarterial fibrinolysis in CRAO. Although plenty of
reports are optimistic, the conclusions from the randomized trial is not so enthusiastic. There is a strong need
for the accurate evaluation of the pathologic changes in the vessels in the organ of sight. It is also necessary
to establish which tests should be performed before the local fibrinolysis is used. These tests should help to
accurate observe the effects of the treatment and also to compare the results from various centers. They
should not delay the fibrynolisys, because there are strong suggestions that the effects are positive only if it
is applied quickly.

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