Vol 17, No 1 (2011)
Review paper
Published online: 2011-04-22
Vascular complications in essential thrombocythaemia
Acta Angiologica 2011;17(1):37-48.
Abstract
Essential thrombocythaemia is a myeloproliferative disorder characterised by both thrombotic and haemorrhagic
events. Proper diagnosis enables administration of adequate therapeutic regimens, which can prevent
occurrence of further thrombotic episodes. Treatment mainly involves cytoreductive and antiplatelet drugs
administered in high-risk patients. New therapeutic agents modulating JAK2 kinase activity can possibly be
used in the future.
Acta Angiol 2011; 17, 1: 37–48
Acta Angiol 2011; 17, 1: 37–48
Keywords: essential thrombocythaemiavascular complicationsarterial thrombosisvenous thrombosisJAK2 V617F mutation