Acute ischaemia of the lower limbs in the course of active ulcerative pancolitis &#8212; a case report and literature review

Joanna Kluz; Rafał Małecki; Paweł Alexewicz; Rajmund Adamiec

Vol 17, No 4 (2011)

Case report

Published online: 2011-12-14

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Acute ischaemia of the lower limbs in the course of active ulcerative pancolitis — a case report and literature review

Joanna Kluz, Rafał Małecki, Paweł Alexewicz, Rajmund Adamiec

Acta Angiologica 2011;17(4):277-285.

Vol 17, No 4 (2011)

Case reports

Published online: 2011-12-14

Abstract

Thromboembolic events represent one of the most serious complications of ulcerative colitis (UC). Two thirds of cases are accounted for by deep vein thrombosis and/or pulmonary embolism. Complications connected with arterial thrombosis are extremely rare and they mostly affect young adults suffering from severe flare-ups of the disease. We present a case of acute ischaemia of the lower limbs in the course of extensive arterial thrombosis in a 28-year-old woman with newly diagnosed UC. The patient was disqualified from surgical thrombectomy due to peripheral localization of vascular changes. Likewise, undertaking local fibrinolysis was impossible because of recent bleeding in the digestive tract. In view of the lack of improvement after conservative treatment of UC and progression of necrosis, a total proctocolectomy was performed. Over the next 14 months of follow-up, the necrotic foot lesions almost completely healed.
Acta Angiol 2011; 17, 4: 277–285

Abstract

Thromboembolic events represent one of the most serious complications of ulcerative colitis (UC). Two thirds of cases are accounted for by deep vein thrombosis and/or pulmonary embolism. Complications connected with arterial thrombosis are extremely rare and they mostly affect young adults suffering from severe flare-ups of the disease. We present a case of acute ischaemia of the lower limbs in the course of extensive arterial thrombosis in a 28-year-old woman with newly diagnosed UC. The patient was disqualified from surgical thrombectomy due to peripheral localization of vascular changes. Likewise, undertaking local fibrinolysis was impossible because of recent bleeding in the digestive tract. In view of the lack of improvement after conservative treatment of UC and progression of necrosis, a total proctocolectomy was performed. Over the next 14 months of follow-up, the necrotic foot lesions almost completely healed.
Acta Angiol 2011; 17, 4: 277–285

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Keywords

arterial thrombosis; lower limbs; ulcerative colitis; acute ischaemia

About this article

Title

Acute ischaemia of the lower limbs in the course of active ulcerative pancolitis — a case report and literature review

Journal

Acta Angiologica

Issue

Vol 17, No 4 (2011)

Article type

Case report

Pages

277-285

Published online

2011-12-14

Bibliographic record

Acta Angiologica 2011;17(4):277-285.

Keywords

arterial thrombosis
lower limbs
ulcerative colitis
acute ischaemia

Authors

Joanna Kluz
Rafał Małecki
Paweł Alexewicz
Rajmund Adamiec