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Testosterone deficiency syndrome - diagnosis and treatment - based on age-related testosterone referent levels
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Abstract
Material and methods. The basis for defining reference values of testosterone concentration in various age groups was a retrospective analysis of 1267 men examined, including 908 treated for TDS at the MAG Medical Center in Warsaw between 2000 and 2007. The therapeutic method was that of inducing T endosynthesis by administering hCG.
Results. The analysis of the patients treated revealed that TDS manifestations relieve at much higher T concentrations than what has been believed so far. T concentrations reached during the therapy resulted from physiological synthesis of testosterone in Leydig’s cells. These results were the basis for establishing reference T concentrations relevant for particular age groups.
Conclusions. The own material presented in the paper shows that the minimal values of testosterone treated as reference values so far at which testosterone treatment is recommended to be initiated, are definitely too low. Introducing T therapy only when the testosterone deficit has resulted in irreversible anatomical changes and lesions seems to be clearly delayed, and is harmful to men.
BPolish Sexology 2010; 8 (1): 1-16
Abstract
Material and methods. The basis for defining reference values of testosterone concentration in various age groups was a retrospective analysis of 1267 men examined, including 908 treated for TDS at the MAG Medical Center in Warsaw between 2000 and 2007. The therapeutic method was that of inducing T endosynthesis by administering hCG.
Results. The analysis of the patients treated revealed that TDS manifestations relieve at much higher T concentrations than what has been believed so far. T concentrations reached during the therapy resulted from physiological synthesis of testosterone in Leydig’s cells. These results were the basis for establishing reference T concentrations relevant for particular age groups.
Conclusions. The own material presented in the paper shows that the minimal values of testosterone treated as reference values so far at which testosterone treatment is recommended to be initiated, are definitely too low. Introducing T therapy only when the testosterone deficit has resulted in irreversible anatomical changes and lesions seems to be clearly delayed, and is harmful to men.
BPolish Sexology 2010; 8 (1): 1-16
Keywords
testosterone; testosterone deficiency syndrome; hCG


Title
Testosterone deficiency syndrome - diagnosis and treatment - based on age-related testosterone referent levels
Journal
Seksuologia Polska (Polish Sexology)
Issue
Article type
Research paper
Pages
1-16
Published online
2010-08-04
Page views
1391
Article views/downloads
50020
Bibliographic record
Seksuologia Polska 2010;8(1):1-16.
Keywords
testosterone
testosterone deficiency syndrome
hCG
Authors
Andrzej Gomuła
Michał Rabijewski