open access

Vol 24, No 4 (2019)
Published online: 2019-07-01
Submitted: 2019-01-21
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Unresectable recurrence malignant sacrococcygeal teratoma in children treated with chemoradiotherapy: Case report and literature review

Yecai Huang, Mei Feng, Jun Yin, Bingyu Fu, Jinyi Lang
DOI: 10.1016/j.rpor.2019.06.002
·
Rep Pract Oncol Radiother 2019;24(4):392-398.

open access

Vol 24, No 4 (2019)
Published online: 2019-07-01
Submitted: 2019-01-21

Abstract

Sacrococcygeal teratoma is the most common germ cell neoplasia that consists of tissues derived from primitive germ layers. Approximately 10–20% of patients are malignant. Because of the high rate of recurrence, treatment strategies for malignant sacrococcygeal teratomas are limited. Hence, we report a case of malignant sacrococcygeal teratoma treated with concurrent chemoradiotherapy plus adjuvant chemotherapy and review the literature. This case report indicates that chemoradiation plus adjuvant chemotherapy may be a treatment option for malignant SCT which is not technically resectable or with residual lesion after surgery.

Abstract

Sacrococcygeal teratoma is the most common germ cell neoplasia that consists of tissues derived from primitive germ layers. Approximately 10–20% of patients are malignant. Because of the high rate of recurrence, treatment strategies for malignant sacrococcygeal teratomas are limited. Hence, we report a case of malignant sacrococcygeal teratoma treated with concurrent chemoradiotherapy plus adjuvant chemotherapy and review the literature. This case report indicates that chemoradiation plus adjuvant chemotherapy may be a treatment option for malignant SCT which is not technically resectable or with residual lesion after surgery.

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Keywords

SCT; MRI; AFP; hCG; PEB; VMAT; Malignant sacrococcygeal teratoma; Chemotherapy; Radiotherapy

About this article
Title

Unresectable recurrence malignant sacrococcygeal teratoma in children treated with chemoradiotherapy: Case report and literature review

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 24, No 4 (2019)

Pages

392-398

Published online

2019-07-01

DOI

10.1016/j.rpor.2019.06.002

Bibliographic record

Rep Pract Oncol Radiother 2019;24(4):392-398.

Keywords

SCT
MRI
AFP
hCG
PEB
VMAT
Malignant sacrococcygeal teratoma
Chemotherapy
Radiotherapy

Authors

Yecai Huang
Mei Feng
Jun Yin
Bingyu Fu
Jinyi Lang

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