open access

Vol 24, No 1 (2019)
Published online: 2019-01-01
Submitted: 2018-03-15
Get Citation

Enhancing radiotherapy effect in breast cancer with nanoparticles: A review

Gustavo R. Sarria, Miguel Ángel Berenguer Francés, Isabel Linares Galiana
DOI: 10.1016/j.rpor.2018.10.003
·
Rep Pract Oncol Radiother 2019;24(1):65-67.

open access

Vol 24, No 1 (2019)
Published online: 2019-01-01
Submitted: 2018-03-15

Abstract

Amongst all efforts for improving oncological management outcomes, nanoparticles enhanced radiation for breast cancer patient's treatment is a novel approach that has grown interest for research in the last decade. Multiple preclinical data has been published, from all around the globe; however, clinical evidence is still insufficient for implementing the method in routine practice and in disease specific management. Gold nanoparticles (AuNP), which may be among the most studed materials, account for the majority of available data; however, some new materials have also been used in preclinical settings.

Without any safety data available at the moment to support an active use, dosimetric in vitro and in vivo information seems to be consistent with a very promising and hopeful panorama for clinical applications. This review evaluates existing dosimetric data in breast cancer tissue, and a probable future impact in treatment choices and patient outcomes, as further investigation is required in a clinical setting.

Abstract

Amongst all efforts for improving oncological management outcomes, nanoparticles enhanced radiation for breast cancer patient's treatment is a novel approach that has grown interest for research in the last decade. Multiple preclinical data has been published, from all around the globe; however, clinical evidence is still insufficient for implementing the method in routine practice and in disease specific management. Gold nanoparticles (AuNP), which may be among the most studed materials, account for the majority of available data; however, some new materials have also been used in preclinical settings.

Without any safety data available at the moment to support an active use, dosimetric in vitro and in vivo information seems to be consistent with a very promising and hopeful panorama for clinical applications. This review evaluates existing dosimetric data in breast cancer tissue, and a probable future impact in treatment choices and patient outcomes, as further investigation is required in a clinical setting.

Get Citation
About this article
Title

Enhancing radiotherapy effect in breast cancer with nanoparticles: A review

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 24, No 1 (2019)

Pages

65-67

Published online

2019-01-01

DOI

10.1016/j.rpor.2018.10.003

Bibliographic record

Rep Pract Oncol Radiother 2019;24(1):65-67.

Authors

Gustavo R. Sarria
Miguel Ángel Berenguer Francés
Isabel Linares Galiana

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