open access

Vol 21, No 6 (2016)
Published online: 2016-11-01
Submitted: 2016-03-17
Get Citation

Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature

Giorgio Spatola, Laura Frosio, Marco Losa, Antonella del Vecchio, Martina Piloni, Pietro Mortini
DOI: 10.1016/j.rpor.2016.09.006
·
Rep Pract Oncol Radiother 2016;21(6):555-559.

open access

Vol 21, No 6 (2016)
Published online: 2016-11-01
Submitted: 2016-03-17

Abstract

Background

Gamma knife radiosurgery is an effective and safe treatment modality in the management of pituitary adenomas. Internal carotid occlusion is a rare but possible complication of Gamma Knife Radiosurgery for lesions within the cavernous sinus.

Aim

To stress the importance of considering the Internal carotid artery as an organ at risk in cavernous sinus invading adenomas and reduce the dose delivered to this structure whenever possible.

Case description

We report two cases of asymptomatic occlusion of the intracavernous segment of the internal carotid artery seven years after treatment in acromegalic patients. After trans-sphenoidal surgery, residual tumour was treated with gamma knife radiosurgery. The maximal doses to the affected artery were higher than 40[[ce:hsp sp="0.25"/]]Gy and the 90% isodose was close to the arterial wall.

Conclusion

Every effort should be done to minimize the radiation dose to the internal carotid artery. If not possible, “hot spots” exceeding the 90% isodose close to this vessel should be avoided.

Abstract

Background

Gamma knife radiosurgery is an effective and safe treatment modality in the management of pituitary adenomas. Internal carotid occlusion is a rare but possible complication of Gamma Knife Radiosurgery for lesions within the cavernous sinus.

Aim

To stress the importance of considering the Internal carotid artery as an organ at risk in cavernous sinus invading adenomas and reduce the dose delivered to this structure whenever possible.

Case description

We report two cases of asymptomatic occlusion of the intracavernous segment of the internal carotid artery seven years after treatment in acromegalic patients. After trans-sphenoidal surgery, residual tumour was treated with gamma knife radiosurgery. The maximal doses to the affected artery were higher than 40[[ce:hsp sp="0.25"/]]Gy and the 90% isodose was close to the arterial wall.

Conclusion

Every effort should be done to minimize the radiation dose to the internal carotid artery. If not possible, “hot spots” exceeding the 90% isodose close to this vessel should be avoided.

Get Citation

Keywords

Pituitary adenoma; Gamma knife radiosurgery; Internal carotid artery occlusion; Growth hormone

About this article
Title

Asymptomatic internal carotid artery occlusion after gamma knife radiosurgery for pituitary adenoma: Report of two cases and review of the literature

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 21, No 6 (2016)

Pages

555-559

Published online

2016-11-01

DOI

10.1016/j.rpor.2016.09.006

Bibliographic record

Rep Pract Oncol Radiother 2016;21(6):555-559.

Keywords

Pituitary adenoma
Gamma knife radiosurgery
Internal carotid artery occlusion
Growth hormone

Authors

Giorgio Spatola
Laura Frosio
Marco Losa
Antonella del Vecchio
Martina Piloni
Pietro Mortini

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl