open access

Vol 18, No 5 (2013)
Original research articles
Published online: 2013-09-01
Submitted: 2012-12-05
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Single high-dose vs. fractionated radiotherapy: Effects on plant growth rates

Marc Guedea, Antoni Castel, Marc Arnalte, Alex Mollera, Victor Muñoz, Ferran Guedea
DOI: 10.1016/j.rpor.2013.07.012
·
Rep Pract Oncol Radiother 2013;18(5):279-285.

open access

Vol 18, No 5 (2013)
Original research articles
Published online: 2013-09-01
Submitted: 2012-12-05

Abstract

Aim

To evaluate the differential effects of fractionated vs. high-dose radiotherapy on plant growth.

Background

Interest in hypofractionated radiotherapy has increased substantially in recent years as tumours (especially of the lung, prostate, and liver) can be irradiated with ever greater accuracy due to technological improvements. The effects of low-dose ionizing radiation on plant growth have been studied extensively, yet few studies have investigated the effect of high-dose, hypofractionated radiotherapy on plant growth development.

Materials and methods

A total of 150 plants from the genus Capsicum annuum were randomized to receive fractionated radiotherapy (5 doses of 10[[ce:hsp sp="0.25"/]]Gy each), single high-dose (SHD) radiotherapy (single 50[[ce:hsp sp="0.25"/]]Gy dose), or no radiotherapy (control group). Irradiation was delivered via linear accelerator and all samples were followed daily for 26 days to assess and compare daily growth.

Results

On day 26, plants in the control, fractionated, and SHD groups had grown to a mean height of 7.55[[ce:hsp sp="0.25"/]]cm, 4.32[[ce:hsp sp="0.25"/]]cm, and 2.94[[ce:hsp sp="0.25"/]]cm, respectively. These differences in overall growth were highly significant (P[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.005). The SHD group showed the least amount of growth.

Conclusions

SHD effectively stunts plant growth and development. Despite the evident differences between plant and animal cells, ionizing radiation is believed to work in a similar manner in all biological cells. These findings highlight the need to continue investigating the use of hypofractionated schemes in humans to improve cancer treatment outcomes.

Abstract

Aim

To evaluate the differential effects of fractionated vs. high-dose radiotherapy on plant growth.

Background

Interest in hypofractionated radiotherapy has increased substantially in recent years as tumours (especially of the lung, prostate, and liver) can be irradiated with ever greater accuracy due to technological improvements. The effects of low-dose ionizing radiation on plant growth have been studied extensively, yet few studies have investigated the effect of high-dose, hypofractionated radiotherapy on plant growth development.

Materials and methods

A total of 150 plants from the genus Capsicum annuum were randomized to receive fractionated radiotherapy (5 doses of 10[[ce:hsp sp="0.25"/]]Gy each), single high-dose (SHD) radiotherapy (single 50[[ce:hsp sp="0.25"/]]Gy dose), or no radiotherapy (control group). Irradiation was delivered via linear accelerator and all samples were followed daily for 26 days to assess and compare daily growth.

Results

On day 26, plants in the control, fractionated, and SHD groups had grown to a mean height of 7.55[[ce:hsp sp="0.25"/]]cm, 4.32[[ce:hsp sp="0.25"/]]cm, and 2.94[[ce:hsp sp="0.25"/]]cm, respectively. These differences in overall growth were highly significant (P[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.005). The SHD group showed the least amount of growth.

Conclusions

SHD effectively stunts plant growth and development. Despite the evident differences between plant and animal cells, ionizing radiation is believed to work in a similar manner in all biological cells. These findings highlight the need to continue investigating the use of hypofractionated schemes in humans to improve cancer treatment outcomes.

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Keywords

Hypofractionation; Single dose; Plants

About this article
Title

Single high-dose vs. fractionated radiotherapy: Effects on plant growth rates

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 18, No 5 (2013)

Pages

279-285

Published online

2013-09-01

DOI

10.1016/j.rpor.2013.07.012

Bibliographic record

Rep Pract Oncol Radiother 2013;18(5):279-285.

Keywords

Hypofractionation
Single dose
Plants

Authors

Marc Guedea
Antoni Castel
Marc Arnalte
Alex Mollera
Victor Muñoz
Ferran Guedea

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