open access

Vol 15, No 6 (2010)
Published online: 2010-11-01
Submitted: 2010-02-03
Get Citation

Simultaneous integrated boost radiotherapy for thyroid cancer

Marta Krystyna Gizynska, Anna Zawadzka, Wojciech Bulski
DOI: 10.1016/j.rpor.2010.10.004
·
Rep Pract Oncol Radiother 2010;15(6):155-160.

open access

Vol 15, No 6 (2010)
Published online: 2010-11-01
Submitted: 2010-02-03

Abstract

Aim

The purpose of this study was to examine the usefulness of using Simultaneous Integrated Boost (SIB) radiotherapy for thyroid cancer treatment.

Background

At our hospital a 3D Conformal RadioTherapy (3D-CRT) technique involving photon and electron beams for the treatment of thyroid cancer was often used.[[ce:cross-ref refid="bib0005"]]1 High dose to the spinal canal was limiting the total dose of such a treatment. After investigation of Intensity Modulated Radiotherapy (IMRT) technique involving seven photon beams for first course of treatment[[ce:cross-ref refid="bib0015"]]3 we decided to examine possibility of reducing treatment fractions by using SIB radiotherapy.

Material and methods

Plans for 10 patients were studied. For each patient, IMRT plan for the first course of treatment (50[[ce:hsp sp="0.25"/]]Gy for PTV), two plans for the second course of treatment (10[[ce:hsp sp="0.25"/]]Gy for BOOST) and a SIB plan (50[[ce:hsp sp="0.25"/]]Gy for PTV, 56[[ce:hsp sp="0.25"/]]Gy for BOOST) were prepared. For all plans, comparisons of dose statistics for the PTV, BOOST, PTV without BOOST (defined as PTV without BOOST with 1[[ce:hsp sp="0.25"/]]cm margin), spinal canal and Patient Outline (Body) was done.

Results

Minimum dose for BOOST is higher in the SIB technique than in the two course treatment. PTV without BOOST receives the same average dose in SIB and the 1st course IMRT – 50.10[[ce:hsp sp="0.25"/]]Gy and 49.84[[ce:hsp sp="0.25"/]]Gy, respectively. In the SIB technique, higher reduction of dose delivered to the spinal canal is possible (27[[ce:hsp sp="0.25"/]]Gy compared with 30[[ce:hsp sp="0.25"/]]Gy).

Conclusion

SIB therapy for thyroid cancer with relation to typical two course treatment is a good proposal of reducing the number of fractions with the same dose for BOOST and PTV without BOOST. Additionally, better sparing of the spinal canal is achieved.

Abstract

Aim

The purpose of this study was to examine the usefulness of using Simultaneous Integrated Boost (SIB) radiotherapy for thyroid cancer treatment.

Background

At our hospital a 3D Conformal RadioTherapy (3D-CRT) technique involving photon and electron beams for the treatment of thyroid cancer was often used.[[ce:cross-ref refid="bib0005"]]1 High dose to the spinal canal was limiting the total dose of such a treatment. After investigation of Intensity Modulated Radiotherapy (IMRT) technique involving seven photon beams for first course of treatment[[ce:cross-ref refid="bib0015"]]3 we decided to examine possibility of reducing treatment fractions by using SIB radiotherapy.

Material and methods

Plans for 10 patients were studied. For each patient, IMRT plan for the first course of treatment (50[[ce:hsp sp="0.25"/]]Gy for PTV), two plans for the second course of treatment (10[[ce:hsp sp="0.25"/]]Gy for BOOST) and a SIB plan (50[[ce:hsp sp="0.25"/]]Gy for PTV, 56[[ce:hsp sp="0.25"/]]Gy for BOOST) were prepared. For all plans, comparisons of dose statistics for the PTV, BOOST, PTV without BOOST (defined as PTV without BOOST with 1[[ce:hsp sp="0.25"/]]cm margin), spinal canal and Patient Outline (Body) was done.

Results

Minimum dose for BOOST is higher in the SIB technique than in the two course treatment. PTV without BOOST receives the same average dose in SIB and the 1st course IMRT – 50.10[[ce:hsp sp="0.25"/]]Gy and 49.84[[ce:hsp sp="0.25"/]]Gy, respectively. In the SIB technique, higher reduction of dose delivered to the spinal canal is possible (27[[ce:hsp sp="0.25"/]]Gy compared with 30[[ce:hsp sp="0.25"/]]Gy).

Conclusion

SIB therapy for thyroid cancer with relation to typical two course treatment is a good proposal of reducing the number of fractions with the same dose for BOOST and PTV without BOOST. Additionally, better sparing of the spinal canal is achieved.

Get Citation

Keywords

SIB; IMRT; Thyroid; TCI

About this article
Title

Simultaneous integrated boost radiotherapy for thyroid cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 15, No 6 (2010)

Pages

155-160

Published online

2010-11-01

DOI

10.1016/j.rpor.2010.10.004

Bibliographic record

Rep Pract Oncol Radiother 2010;15(6):155-160.

Keywords

SIB
IMRT
Thyroid
TCI

Authors

Marta Krystyna Gizynska
Anna Zawadzka
Wojciech Bulski

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl