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Gliosarcoma: A rare primary CNS tumor. Presentation of two cases
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Abstract
Introduction
Gliosarcoma is a very rare primary mixed tumor in the central nervous system, with a biphasic pattern consisting of glial and malignant mesenchymal elements. Its onset is between the fourth and sixth decade of life, and it has a male/female ratio of 1.8/1. Here we present two cases of Gliosarcoma treated in our department.
Discussion
The monoclonal or biclonal origin of its biphasic nature is still subject to debate; hence the importance of its diagnosis and histogenesis.
Results
Standard treatment consists in surgical resection of the tumor followed in some cases by external radiotherapy and chemotherapy.
Abstract
Introduction
Gliosarcoma is a very rare primary mixed tumor in the central nervous system, with a biphasic pattern consisting of glial and malignant mesenchymal elements. Its onset is between the fourth and sixth decade of life, and it has a male/female ratio of 1.8/1. Here we present two cases of Gliosarcoma treated in our department.
Discussion
The monoclonal or biclonal origin of its biphasic nature is still subject to debate; hence the importance of its diagnosis and histogenesis.
Results
Standard treatment consists in surgical resection of the tumor followed in some cases by external radiotherapy and chemotherapy.
Keywords
Gliosarcoma; Two cases report
About this articleTitle
Gliosarcoma: A rare primary CNS tumor. Presentation of two cases
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
98-102
Published online
2010-07-01
DOI
10.1016/j.rpor.2010.05.003
Bibliographic record
Rep Pract Oncol Radiother 2010;15(4):98-102.
Keywords
Gliosarcoma
Two cases report
Authors
José Pardo
Mauricio Murcia
Felip García
Arnaldo Alvarado