Vol 15, No 4 (2010)
Published online: 2010-07-01

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Gliosarcoma: A rare primary CNS tumor. Presentation of two cases

José Pardo1, Mauricio Murcia1, Felip García2, Arnaldo Alvarado1
DOI: 10.1016/j.rpor.2010.05.003
Rep Pract Oncol Radiother 2010;15(4):98-102.

Abstract

Introduction

Gliosarcoma is a very rare primary mixed tumor in the central nervous system, with a biphasic pattern consisting of glial and malignant mesenchymal elements. Its onset is between the fourth and sixth decade of life, and it has a male/female ratio of 1.8/1. Here we present two cases of Gliosarcoma treated in our department.

Discussion

The monoclonal or biclonal origin of its biphasic nature is still subject to debate; hence the importance of its diagnosis and histogenesis.

Results

Standard treatment consists in surgical resection of the tumor followed in some cases by external radiotherapy and chemotherapy.

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Reports of Practical Oncology and Radiotherapy