open access

Vol 11, No 2 (2006)
Published online: 2006-01-01
Submitted: 2005-06-30
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Dissemination of malignant gliomas beyond the central nervous system

Maria L. Pamucka, Lidia Czopkiewicz, Ewa Skrzypczyńska, Piotr Tokar
DOI: 10.1016/S1507-1367(06)71055-0
·
Rep Pract Oncol Radiother 2006;11(2):101-104.

open access

Vol 11, No 2 (2006)
Published online: 2006-01-01
Submitted: 2005-06-30

Abstract

Background

Gliomas are the most frequently diagnosed primary intracranial tumours in adults. This group incorporates astrocytomas, oligodendrogliomas and ependymomas. Glioma treatment in adults usually means surgery and radiotherapy, and in the case of poorly differentiated tumours, chemotherapy may also be applied. Failures in the treatment of malignant gliomas are mostly local recurrences, intracranial dissemination and, very seldom, metastases beyond the central nervous system.

Aim

The aim of this paper was to present two instances of extraneural dissemination in cases of malignant glioma of the brain.

Materials/Methods

Two patients with dissemination of malignant glioma were diagnosed and treated in our department during the last 20 years.

Results

Treatment effects were poor.

Conclusions

Extraneural brain tumour dissemination is infrequent and their treatment remains an unsolved problem. Treatment is similar to that of primary glioma, especially in cases with high dynamics.

Neither chemotherapy nor radiotherapy are able to produce even a short term palliative effect.

Abstract

Background

Gliomas are the most frequently diagnosed primary intracranial tumours in adults. This group incorporates astrocytomas, oligodendrogliomas and ependymomas. Glioma treatment in adults usually means surgery and radiotherapy, and in the case of poorly differentiated tumours, chemotherapy may also be applied. Failures in the treatment of malignant gliomas are mostly local recurrences, intracranial dissemination and, very seldom, metastases beyond the central nervous system.

Aim

The aim of this paper was to present two instances of extraneural dissemination in cases of malignant glioma of the brain.

Materials/Methods

Two patients with dissemination of malignant glioma were diagnosed and treated in our department during the last 20 years.

Results

Treatment effects were poor.

Conclusions

Extraneural brain tumour dissemination is infrequent and their treatment remains an unsolved problem. Treatment is similar to that of primary glioma, especially in cases with high dynamics.

Neither chemotherapy nor radiotherapy are able to produce even a short term palliative effect.

Get Citation

Keywords

brain tumour; malignant glioma; dissemination of malignant gliomas

About this article
Title

Dissemination of malignant gliomas beyond the central nervous system

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 11, No 2 (2006)

Pages

101-104

Published online

2006-01-01

DOI

10.1016/S1507-1367(06)71055-0

Bibliographic record

Rep Pract Oncol Radiother 2006;11(2):101-104.

Keywords

brain tumour
malignant glioma
dissemination of malignant gliomas

Authors

Maria L. Pamucka
Lidia Czopkiewicz
Ewa Skrzypczyńska
Piotr Tokar

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