Vol 9, No 7 (2004)
Published online: 2004-01-01

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Sentinel lymph node in colorectal cancer

Zbigniew Lorenc1, Jacek Starzewski1, Danuta Kokocińska1, Monika Brzezińska1, Mieszko Opiłka1
DOI: 10.1016/S1507-1367(04)71041-X
Rep Pract Oncol Radiother 2004;9(7):307-311.

Abstract

Introduction

In the paper a review of the literature on the usefulness of the sentinel lymph node (SLN) identification in clinical staging of the colorectal cancer was performed. Studies conducted In different surgical departments were analyzed. Crucial elements in prognosis in patients with colorectal cancer and mistakes made in clinical staging of theses patients were pointed out. Lymph nodes metastases warrants the adjuvant therapy and improves results of treatment. The diagnostic methods used at the moment are not very accurate in clinical staging, therefore a search for the new methods, which would enable more precise staging and at the same time the suitable treatment is being made.

Material and methods

The sentinel node concept and the benefits of its identification are discussed. Techniques of the SLN dying (dyes, application) are presented.

Results

The diagnostic efficacy of the method in different studies and the detailed pathological examination (haematoxylin-eosin, immunohistochemistry, molecular techniques) is being analyzed. Positive and false negative results in the studies are evaluated.

Conclusion

The usefulness of the method and application in the clinical setting in colorectal cancer is shown, still further studies are needed.

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Reports of Practical Oncology and Radiotherapy