open access

Vol 9, No 7 (2004)
Published online: 2004-01-01
Submitted: 2004-05-13
Get Citation

Sentinel lymph node in colorectal cancer

Zbigniew Lorenc, Jacek Starzewski, Danuta Kokocińska, Monika Brzezińska, Mieszko Opiłka
DOI: 10.1016/S1507-1367(04)71041-X
·
Rep Pract Oncol Radiother 2004;9(7):307-311.

open access

Vol 9, No 7 (2004)
Published online: 2004-01-01
Submitted: 2004-05-13

Abstract

Introduction

In the paper a review of the literature on the usefulness of the sentinel lymph node (SLN) identification in clinical staging of the colorectal cancer was performed. Studies conducted In different surgical departments were analyzed. Crucial elements in prognosis in patients with colorectal cancer and mistakes made in clinical staging of theses patients were pointed out. Lymph nodes metastases warrants the adjuvant therapy and improves results of treatment. The diagnostic methods used at the moment are not very accurate in clinical staging, therefore a search for the new methods, which would enable more precise staging and at the same time the suitable treatment is being made.

Material and methods

The sentinel node concept and the benefits of its identification are discussed. Techniques of the SLN dying (dyes, application) are presented.

Results

The diagnostic efficacy of the method in different studies and the detailed pathological examination (haematoxylin-eosin, immunohistochemistry, molecular techniques) is being analyzed. Positive and false negative results in the studies are evaluated.

Conclusion

The usefulness of the method and application in the clinical setting in colorectal cancer is shown, still further studies are needed.

Abstract

Introduction

In the paper a review of the literature on the usefulness of the sentinel lymph node (SLN) identification in clinical staging of the colorectal cancer was performed. Studies conducted In different surgical departments were analyzed. Crucial elements in prognosis in patients with colorectal cancer and mistakes made in clinical staging of theses patients were pointed out. Lymph nodes metastases warrants the adjuvant therapy and improves results of treatment. The diagnostic methods used at the moment are not very accurate in clinical staging, therefore a search for the new methods, which would enable more precise staging and at the same time the suitable treatment is being made.

Material and methods

The sentinel node concept and the benefits of its identification are discussed. Techniques of the SLN dying (dyes, application) are presented.

Results

The diagnostic efficacy of the method in different studies and the detailed pathological examination (haematoxylin-eosin, immunohistochemistry, molecular techniques) is being analyzed. Positive and false negative results in the studies are evaluated.

Conclusion

The usefulness of the method and application in the clinical setting in colorectal cancer is shown, still further studies are needed.

Get Citation

Keywords

colorectal cancer; sentinel lymph node; advanced cancer stage

About this article
Title

Sentinel lymph node in colorectal cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 9, No 7 (2004)

Pages

307-311

Published online

2004-01-01

DOI

10.1016/S1507-1367(04)71041-X

Bibliographic record

Rep Pract Oncol Radiother 2004;9(7):307-311.

Keywords

colorectal cancer
sentinel lymph node
advanced cancer stage

Authors

Zbigniew Lorenc
Jacek Starzewski
Danuta Kokocińska
Monika Brzezińska
Mieszko Opiłka

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl