open access

Vol 9, No 6 (2004)
Published online: 2004-01-01
Submitted: 2004-04-06
Get Citation

Immunohistochemical staining in thyroid carcinoma: has it become a standard?

Dariusz Lange, Barbara Nikiel, Jerzy Nożynski
DOI: 10.1016/S1507-1367(04)71037-8
·
Rep Pract Oncol Radiother 2004;9(6):257-260.

open access

Vol 9, No 6 (2004)
Published online: 2004-01-01
Submitted: 2004-04-06

Abstract

This paper describes results of immunohistochemical studies, used to diagnose primary and metastatic thyroid tumours. We discuss differential diagnosis of medullary thyroid carcinoma and c-cell hyperplasia in patients with RET protooncogene mutation, who had undergone prophylactic thyroidectomy. In particular, we focus on the possible immunohistochemical differentiation of follicular thyroid tumours. We discuss technical issues encountered in applying immunohistochemical methods as well as the commonest errors in the inter-pretation of results. In conclusion, we indicate areas of thyroid pathology where immunohistochemical staining appears absolutely necessary, and others where such methods can merely assist in reaching final diagnostic decision.

Abstract

This paper describes results of immunohistochemical studies, used to diagnose primary and metastatic thyroid tumours. We discuss differential diagnosis of medullary thyroid carcinoma and c-cell hyperplasia in patients with RET protooncogene mutation, who had undergone prophylactic thyroidectomy. In particular, we focus on the possible immunohistochemical differentiation of follicular thyroid tumours. We discuss technical issues encountered in applying immunohistochemical methods as well as the commonest errors in the inter-pretation of results. In conclusion, we indicate areas of thyroid pathology where immunohistochemical staining appears absolutely necessary, and others where such methods can merely assist in reaching final diagnostic decision.

Get Citation

Keywords

thyroid; carcinoma; immunohistochemistry

About this article
Title

Immunohistochemical staining in thyroid carcinoma: has it become a standard?

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 9, No 6 (2004)

Pages

257-260

Published online

2004-01-01

DOI

10.1016/S1507-1367(04)71037-8

Bibliographic record

Rep Pract Oncol Radiother 2004;9(6):257-260.

Keywords

thyroid
carcinoma
immunohistochemistry

Authors

Dariusz Lange
Barbara Nikiel
Jerzy Nożynski

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl