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Vol 14, No 3 (2017)
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Duloxetine in the treatment of depression with somatic and psychic pain

Sławomir Murawiec
Psychiatria 2017;14(3):144-149.

open access

Vol 14, No 3 (2017)
Prace kazuistyczne

Abstract

The study presents two case reports of patients treated with duloxetine. Duloxetine belongs to the group of antidepressants with dual action on neurotransmitters — selective serotonin and noradrenaline selective reuptake inhibitors. The effect of duloxetine on both these neurotransmitters is relatively balanced and achievable at standard daily doses. The first case discusses the treatment of patients with depression and comorbid psoriatic arthritis. The use of citalopram in this patient has improved the depressive symptoms, but the change of treatment from citalopram to duloxetine has made it possible to alleviate both depressive symptoms and somatic pain. In the second case, the extrapolation of data on the effect of duloxetine on somatic pain on the phenomenon of mental pain was made. The patient complaining about the psychic pain caused by past social rejection in the several months of depression treatment reported alleviation of psychic pain during duloxetine pharmacotherapy. Previous treatment of this patient with escitalopram brought improvement to the mood, but did not eliminate complaints about psychic pain.

Abstract

The study presents two case reports of patients treated with duloxetine. Duloxetine belongs to the group of antidepressants with dual action on neurotransmitters — selective serotonin and noradrenaline selective reuptake inhibitors. The effect of duloxetine on both these neurotransmitters is relatively balanced and achievable at standard daily doses. The first case discusses the treatment of patients with depression and comorbid psoriatic arthritis. The use of citalopram in this patient has improved the depressive symptoms, but the change of treatment from citalopram to duloxetine has made it possible to alleviate both depressive symptoms and somatic pain. In the second case, the extrapolation of data on the effect of duloxetine on somatic pain on the phenomenon of mental pain was made. The patient complaining about the psychic pain caused by past social rejection in the several months of depression treatment reported alleviation of psychic pain during duloxetine pharmacotherapy. Previous treatment of this patient with escitalopram brought improvement to the mood, but did not eliminate complaints about psychic pain.

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Keywords

duloxetine, somatic pain, psychic pain

About this article
Title

Duloxetine in the treatment of depression with somatic and psychic pain

Journal

Psychiatria (Psychiatry)

Issue

Vol 14, No 3 (2017)

Pages

144-149

Bibliographic record

Psychiatria 2017;14(3):144-149.

Keywords

duloxetine
somatic pain
psychic pain

Authors

Sławomir Murawiec

References (18)
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