open access

Vol 12, No 3 (2015)
Review paper
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Quetiapine Sustained-Release — upgrade in the treatment of bipolar disorder

Tomasz Sobów
Psychiatria 2015;12(3):137-141.

open access

Vol 12, No 3 (2015)
Prace poglądowe - nadesłane

Abstract

Quetiapine is an effective antipsychotic drug with proven efficacy in the treatment of schizophrenia and bipolar disorder as well as recurrent depression and generalized anxiety disorder. Quetiapine with slow-release formulation (SR) allows once-daily schedule, which might be of importance considering treatment compliance. In clinical trials a comparable efficacy of both formulations has been shown in the treatment of bipolar disorder. That resulted in quetiapine SR registration for the treatment of mania, bipolar depression as well as in the maintenance treatment of bipolar disorder. Clinical trials and physicians’ observations indicate a possibility of faster therapeutic dosing and general better tolerance of SR formulation as compared to IR. Quetiapine SR is particularly recommended for patients who, while benefiting from treatment in general, complain on daytime sedation.

Abstract

Quetiapine is an effective antipsychotic drug with proven efficacy in the treatment of schizophrenia and bipolar disorder as well as recurrent depression and generalized anxiety disorder. Quetiapine with slow-release formulation (SR) allows once-daily schedule, which might be of importance considering treatment compliance. In clinical trials a comparable efficacy of both formulations has been shown in the treatment of bipolar disorder. That resulted in quetiapine SR registration for the treatment of mania, bipolar depression as well as in the maintenance treatment of bipolar disorder. Clinical trials and physicians’ observations indicate a possibility of faster therapeutic dosing and general better tolerance of SR formulation as compared to IR. Quetiapine SR is particularly recommended for patients who, while benefiting from treatment in general, complain on daytime sedation.

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Keywords

bipolar disorder, treatment, quetiapine, efficacy, safety

About this article
Title

Quetiapine Sustained-Release — upgrade in the treatment of bipolar disorder

Journal

Psychiatria (Psychiatry)

Issue

Vol 12, No 3 (2015)

Article type

Review paper

Pages

137-141

Bibliographic record

Psychiatria 2015;12(3):137-141.

Keywords

bipolar disorder
treatment
quetiapine
efficacy
safety

Authors

Tomasz Sobów

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