open access

Vol 6, No 1 (2009)
Research paper
Published online: 2009-03-17
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Working memory, executive function and depressive symptoms in pathological obesity

Marcin Jaracz, Maciej Bieliński, Roman Junik, Stanisław Dąbrowiecki, Wojciech Szczęsny, Jacek Chojnowski, Alina Borkowska
Psychiatria 2009;6(1):9-14.

open access

Vol 6, No 1 (2009)
Prace oryginalne - nadesłane
Published online: 2009-03-17

Abstract


Introduction. Pathological obesity is a disorder with complex etiology. The main brain-related etiopathological factors of obesity are dysfunction of prefrontal cortex and deficit of serotonin. Several studies have revealed a relation between obesity and occurrence of cognitive deficits and greater intensity of depressive symptoms. The aim of the study was to assess cognitive functioning and depressive symptoms in pathologically obese subjects in polish population.
Material and methods. Seventy five subjects with pathological obesity (BMI > 30) - 16 male and 59 female, aged 39 ± 11 were enrolled in the study. Control group consisted of 75 age, sex and education years matched healthy subjects. Cognitive assessment was made with Wisconsin Card Sorting Test (WCST). Depressive symptoms were assessed with 21 item Beck Depression Inventory and 17 item Hamilton Depression Rating Scale.
Results. Obese subjects performed significantly worse on all measures of WCST. Symptoms of at least mild depression in over half of obese subjects were observed. A correlation between depression severity, BMI score and a level of performance in WCST was observed.
Conclusions. Pathological obesity is related with deficits of working memory and executive function and greater severity of depressive symptoms.

Abstract


Introduction. Pathological obesity is a disorder with complex etiology. The main brain-related etiopathological factors of obesity are dysfunction of prefrontal cortex and deficit of serotonin. Several studies have revealed a relation between obesity and occurrence of cognitive deficits and greater intensity of depressive symptoms. The aim of the study was to assess cognitive functioning and depressive symptoms in pathologically obese subjects in polish population.
Material and methods. Seventy five subjects with pathological obesity (BMI > 30) - 16 male and 59 female, aged 39 ± 11 were enrolled in the study. Control group consisted of 75 age, sex and education years matched healthy subjects. Cognitive assessment was made with Wisconsin Card Sorting Test (WCST). Depressive symptoms were assessed with 21 item Beck Depression Inventory and 17 item Hamilton Depression Rating Scale.
Results. Obese subjects performed significantly worse on all measures of WCST. Symptoms of at least mild depression in over half of obese subjects were observed. A correlation between depression severity, BMI score and a level of performance in WCST was observed.
Conclusions. Pathological obesity is related with deficits of working memory and executive function and greater severity of depressive symptoms.
Get Citation

Keywords

obesity; depression; working memory; executive function

About this article
Title

Working memory, executive function and depressive symptoms in pathological obesity

Journal

Psychiatria (Psychiatry)

Issue

Vol 6, No 1 (2009)

Article type

Research paper

Pages

9-14

Published online

2009-03-17

Bibliographic record

Psychiatria 2009;6(1):9-14.

Keywords

obesity
depression
working memory
executive function

Authors

Marcin Jaracz
Maciej Bieliński
Roman Junik
Stanisław Dąbrowiecki
Wojciech Szczęsny
Jacek Chojnowski
Alina Borkowska

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