open access

Vol 6, No 1 (2009)
Research paper
Published online: 2009-03-17
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Long-term, 12-month impact of olanzapine treatment on psychosocial functioning of schizophrenic patients

Bartosz Łoza, Paweł Bednarski, Joanna Grzesiewska, Maja Polikowska, Anna Mosiołek, Iwona Patejuk-Mazurek, Rafał Wójcik
Psychiatria 2009;6(1):1-8.

open access

Vol 6, No 1 (2009)
Prace oryginalne - nadesłane
Published online: 2009-03-17

Abstract

Introduction. Long-term, 12-month effects of olanzapine treatment were evaluated in a sample of 1053 schizophrenic patients.
Material and methods. A repeated-measure, naturalistic, prospective design was used. Data were collected at baseline and at three-month follow-ups. Patients were switched from various antipsychotics because of insufficient response and/or marked intolerance. Several psychosocial functioning dimensions were evaluated based on Clinical Global Impression scale.
Results. After 12 months, significant improvement in psychosocial functioning was found. Similar patterns of improvements in family relationships, occupational engagement, and other distorted social domains were established.
Conclusions. Long-term olanzapine treatment appeared to be effective method for psychosocial intervention among patients with schizophrenia.

Abstract

Introduction. Long-term, 12-month effects of olanzapine treatment were evaluated in a sample of 1053 schizophrenic patients.
Material and methods. A repeated-measure, naturalistic, prospective design was used. Data were collected at baseline and at three-month follow-ups. Patients were switched from various antipsychotics because of insufficient response and/or marked intolerance. Several psychosocial functioning dimensions were evaluated based on Clinical Global Impression scale.
Results. After 12 months, significant improvement in psychosocial functioning was found. Similar patterns of improvements in family relationships, occupational engagement, and other distorted social domains were established.
Conclusions. Long-term olanzapine treatment appeared to be effective method for psychosocial intervention among patients with schizophrenia.
Get Citation

Keywords

schizophrenia; olanzapine; antipsychotic switch; long-term treatment; psychosocial dimension

About this article
Title

Long-term, 12-month impact of olanzapine treatment on psychosocial functioning of schizophrenic patients

Journal

Psychiatria (Psychiatry)

Issue

Vol 6, No 1 (2009)

Article type

Research paper

Pages

1-8

Published online

2009-03-17

Bibliographic record

Psychiatria 2009;6(1):1-8.

Keywords

schizophrenia
olanzapine
antipsychotic switch
long-term treatment
psychosocial dimension

Authors

Bartosz Łoza
Paweł Bednarski
Joanna Grzesiewska
Maja Polikowska
Anna Mosiołek
Iwona Patejuk-Mazurek
Rafał Wójcik

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