Long-term remission after erlotinib therapy in an elderly patient with advanced non-small-cell lung cancer. Case report and conclusions for clinical practice

Renata Duchnowska, Anna Siemiątkowska, Bartłomiej Grala, Marta Smoter
Pneumonol Alergol Pol 2008;76(6):451-455.

open access

Vol 76, No 6 (2008)
CASE REPORTS
Published online: 2008-10-31
Submitted: 2013-02-22

Abstract

Small molecule tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR) - gefitinib and erlotinib - have recently been used as a therapeutic option in advanced non-small cell lung cancer (NSCLC) patients relapsing after first- or second-line chemotherapy. We report here a case of long-term remission in an elderly, non-smoking woman with advanced NSCLC after chemotherapy failure, who was selected for erlotinib therapy using demographic and clinical criteria. Based on this example and on the literature data we discuss the need for careful patient selection for this new therapeutic method.

Keywords

non-small cell lung cancer; erlotinib; targeted therapies

About this article
Title

Long-term remission after erlotinib therapy in an elderly patient with advanced non-small-cell lung cancer. Case report and conclusions for clinical practice

Journal

Pneumologia i Alergologia Polska

Issue

Vol 76, No 6 (2008)

Pages

451-455

Published online

2008-10-31

Bibliographic record

Pneumonol Alergol Pol 2008;76(6):451-455.

Keywords

non-small cell lung cancer
erlotinib
targeted therapies

Authors

Renata Duchnowska
Anna Siemiątkowska
Bartłomiej Grala
Marta Smoter

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