Vol 13, No 5 (2017)
Review paper
Published online: 2017-11-15
Abiraterone acetate in the treatment of patients with metastatic prostate cancer
DOI: 10.5603/OCP.2017.0028
Oncol Clin Pract 2017;13(5):220-224.
Abstract
For a long time, systemic treatment of patients diagnosed with metastatic castration-resistant prostate cancer
(mCRPC) has been based solely on chemotherapy (docetaxel). The introduction of novel endocrine agents has
significantly improved outcomes of mCRPC patients. Till date, abirateron acetate is the only drug with confirmed
activity (significant improvement in overall survival) in both clinical settings: castration resistance (pre or post
chemotherapy) and castration sensitivity. The article is aimed to summarize current knowledge on the place and
role of abiraterone acetate in palliative systemic treatment of metastatic prostate cancer patients.
Keywords: prostate cancerabirateronecastration resistancemetastasesendocrine treatment
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