open access

Vol 2, No 1 (2006)
Review paper
Published online: 2006-01-06
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Postoperatively administered therapy in glioblastoma multiforme: impasse or progress

Bogdan Gliński, Magdalena Ząbek, Jacek Urbański
Onkol. Prak. Klin 2006;2(1):1-5.

open access

Vol 2, No 1 (2006)
REVIEW ARTICLES
Published online: 2006-01-06

Abstract

The prognosis of patients with glioblastoma remains extremely poor, this tumour still present the supreme challenge to the local modes of therapy. Clinical research concerning the role and place of radiation therapy has been very active for the last thirty years. All the concepts developed in the laboratories of radiobiology were explored: radiosensitisation of hypoxic tumours, particle therapy, irradiation in hyperbaric oxygen conditions, hyperfractionated radiotherapy and local dose escalation using stereotactic techniques (radiosurgery) or brachytherapy. All this approaches failed to improve significantly the results of treatment of these patients.

Abstract

The prognosis of patients with glioblastoma remains extremely poor, this tumour still present the supreme challenge to the local modes of therapy. Clinical research concerning the role and place of radiation therapy has been very active for the last thirty years. All the concepts developed in the laboratories of radiobiology were explored: radiosensitisation of hypoxic tumours, particle therapy, irradiation in hyperbaric oxygen conditions, hyperfractionated radiotherapy and local dose escalation using stereotactic techniques (radiosurgery) or brachytherapy. All this approaches failed to improve significantly the results of treatment of these patients.
Get Citation

Keywords

glioblastoma; radiotherapy; neurosurgery

About this article
Title

Postoperatively administered therapy in glioblastoma multiforme: impasse or progress

Journal

Oncology in Clinical Practice

Issue

Vol 2, No 1 (2006)

Article type

Review paper

Pages

1-5

Published online

2006-01-06

Bibliographic record

Onkol. Prak. Klin 2006;2(1):1-5.

Keywords

glioblastoma
radiotherapy
neurosurgery

Authors

Bogdan Gliński
Magdalena Ząbek
Jacek Urbański

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