Vol 6, No 3 (2010)
Review paper
Published online: 2010-08-27
The role of ultrasound, computed tomography, and magnetic resonance imaging in the diagnostics of pancreatic tumors
Onkol. Prak. Klin 2010;6(3):104-112.
Abstract
Advances in diagnostic radiology allow detection of small pancreatic lesions, their character, localization,
and assessment of preoperative staging. This information has been crucial in the advancement of
oncologic therapies aimed at treating pancreatic malignancies. While planning the diagnostic process it
is important to keep in mind that while all the diagnostic modalities have their attributes, they do however,
have their limitations. This publication will review the role of ultrasound, computed tomography, and
magnetic resonance imaging in the diagnosis of pancreatic tumors.
Onkol. Prak. Klin. 2010; 6, 3: 104–112
Onkol. Prak. Klin. 2010; 6, 3: 104–112
Keywords: pancreatic tumorspancreatic malignanciesUSultrasoundCTcomputed tomographyMRImagnetic resonance imaging
References
- Taylor KJ, Buchin PJ, Viscomi GN, et al. Ultrasonographic scanning of the pancreas. Prospective study of clinical results. Radiology. 1981; 138(1): 211–213.
- DiMagno EP. Pancreatic cancer: a continuing diagnostic dilemma. Ann Intern Med. 1979; 90(5): 847–848.
- de Graaff CS, Taylor KJ, Simonds BD, et al. Gray-scale echography of the pancreas. Re-evaluation of normal size. Radiology. 1978; 129(1): 157–161.
- Kremer H. Diagnostyka ultrasonograficzna. Urban&Partner, Wrocław 2004: 152–157.
- Thoeni RF, Mueller-Lisse UG, Chan R, et al. Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity. Radiology. 2000; 214(2): 483–490.
- Theoharides TC. Mast cells and pancreatic cancer. N Engl J Med. 2008; 358(17): 1860–1861.
- Prokop M. Spiralna i wielorzędowa tomografia komputerowa. Medipage, Warszawa 2007: 508–523.
- Warshaw AL, Fernández-del Castillo C. Pancreatic carcinoma. N Engl J Med. 1992; 326(7): 455–465.
- Prokesch RW, Chow LC, Beaulieu CF, et al. Isoattenuating pancreatic adenocarcinoma at multi-detector row CT: secondary signs. Radiology. 2002; 224(3): 764–768.
- Horton KM, Fishman EK. Adenocarcinoma of the pancreas: CT imaging. Radiol Clin North Am. 2002; 40(6): 1263–1272.
- Diehl SJ, Lehmann KJ, Sadick M, et al. Pancreatic cancer: value of dual-phase helical CT in assessing resectability. Radiology. 1998; 206(2): 373–378.
- Lu DS, Reber HA, Krasny RM, et al. Local staging of pancreatic cancer: criteria for unresectability of major vessels as revealed by pancreatic-phase, thin-section helical CT. AJR Am J Roentgenol. 1997; 168(6): 1439–1443.
- Takahashi N, Brown JJ. MRI of the pancreas. Applied Radiology. 2002: 31.
- Nishiharu T, Yamashita Y, Abe Y, et al. Local extension of pancreatic carcinoma: assessment with thin-section helical CT versus with breath-hold fast MR imaging--ROC analysis. Radiology. 1999; 212(2): 445–452.
- Kloppel G, Schroder S, Heitz PU. Histopathology and immunopathology of pancreatic endocrine tumors. W: Mignon M., Jensen R.T. (red.). Endocrine tumors of the pancreas: recent advances in research and management. Series: Frontiers in Gastrointestinal Research. 1995; 23: 99–120.
- Pearse AG. The APUD concept and hormone production. Clin Endocrinol Metab. 1980; 9(2): 211–222.
- Davis SL, Brooke RJ, Kamaya A. Islet-cell tumors of the pancreas: spectrum of MDCT findings. A pictorial essay. Applied Radiology. 2009; 38: 11.
- Klöppel G, Heitz PU. Pancreatic endocrine tumors. Pathol Res Pract. 1988; 183(2): 155–168.
- Heitz PU, Kasper M, Klöppel G, et al. Pancreatic endocrine tumors. Hum Pathol. 1982; 13(3): 263–271.
- Jensen RT. Annals of Oncology. 1999; 10(4suppl): 170–176.
- Soga J, Yakuwa Y, Osaka M. Insulinoma/hypoglycemic syndrome: a statistical evaluation of 1085 reported cases of a Japanese series. J Exp Clin Cancer Res. 1998; 17(4): 379–388.
- Fajans SS, Vinik AI. Insulin-producing islet cell tumors. Endocrinol Metab Clin North Am. 1989; 18(1): 45–74.
- Broughan TA, Leslie JD, Soto JM, et al. Pancreatic islet cell tumors. Surgery. 1986; 99(6): 671–678.
- Haubrich WS, Berk JE. Endocrine tumors of the pancreas. Bockus Gastroenterology. W.B. Saunders, Philadelphia 1995: 3002–3034.
- Phan G. Surgical experience with pancreatic and peripancreatic neuroendocrine tumors: review of 125 patients, Journal of Gastrointestinal Surgery. 1998; 2(5): 473–482.
- Boukhman MP, Karam JM, Shaver J, et al. Localization of insulinomas. Arch Surg. 1999; 134(8): 818–822.
- Galiber AK, Reading CC, Charboneau JW, et al. Localization of pancreatic insulinoma: comparison of pre- and intraoperative US with CT and angiography. Radiology. 1988; 166(2): 405–408.
- Aslam R, Yee J. MDCT of pancreatic masses. Applied Radiology. 2006; 35: 4.
- Fidler JL, Fletcher JG, Reading CC, et al. Preoperative detection of pancreatic insulinomas on multiphasic helical CT. AJR Am J Roentgenol. 2003; 181(3): 775–780.
- Gouya H, Vignaux O, Augui J, et al. CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR Am J Roentgenol. 2003; 181(4): 987–992.
- Haubrich WS, Berk JE. Endocrine Tumors of the pancreas. Bockus Gastroenterology. Wyd. W.B. Saunders, Philadelphia 1995: 3002–3034.
- Keogan MT, McDermott VG, Paulson EK, et al. Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification. Radiology. 1997; 205(2): 513–518.
- Lee DS. R. Brooke R.J., Kamaya A. Islet-cell tumors of the pancreas: Spectrum of MDCT findings. A pictorial essay. Applied Radiology. 2009; 38: 11.
- Noone TC, Hosey J, Firat Z, et al. Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. Best Pract Res Clin Endocrinol Metab. 2005; 19(2): 195–211.
- del Castillo FC, Warshaw AL. Current management of cystic neoplasms of the pancreas. Adv Surg. 2000; 34: 237–248.
- Curry CA, Eng J, Horton KM, et al. CT of primary cystic pancreatic neoplasms: can CT be used for patient triage and treatment? AJR Am J Roentgenol. 2000; 175(1): 99–103.
- Brant WE. Podstawy diagnostyki radiologicznej. Tom 3. Medipage, Warszawa 2008: 860–870.
- Procacci C, Graziani R, Bicego E, et al. Intraductal mucin-producing tumors of the pancreas: imaging findings. Radiology. 1996; 198(1): 249–257.
- Friedman AC, Lichtenstein JE, Dachman AH. Cystic neoplasms of pancreas. Radiology. 1983; 149: 45–50.
- Ros PR, Hamrick-Turner JE, Chiechi MV, et al. Cystic masses of the pancreas. Radiographics. 1992; 12(4): 673–686.
- Brugge WR, Lauwers GY, Sahani D, et al. Cystic neoplasms of the pancreas. N Engl J Med. 2004; 351(12): 1218–1226.
- Ferreira AM, Vaz A, Viana M, et al. Case 136: intraductal papillary mucinous tumor (main duct type) of the pancreas. Radiology. 2008; 248(2): 695–697.
- Vullierme MP, Giraud-Cohen M, Hammel P, et al. Malignant intraductal papillary mucinous neoplasm of the pancreas: in situ versus invasive carcinoma surgical resectability. Radiology. 2007; 245(2): 483–490.
- Merkle EM, Bender GN, Brambs HJ. Imaging findings in pancreatic lymphoma: differential aspects. AJR Am J Roentgenol. 2000; 174(3): 671–675.
- Scatarige JC, Horton KM, Sheth S, et al. Pancreatic parenchymal metastases: observations on helical CT. AJR Am J Roentgenol. 2001; 176(3): 695–699.