open access

Vol 15, No 4 (2019)
Case report
Published online: 2019-08-21
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Hodgkin’s lymphoma with multifocal Staphylococcus aureus infection in a 29-year-old male — a case study

Katarzyna Kryszczyszyn-Musialik, Grzegorz Słomian, Krzysztof Musialik
DOI: 10.5603/OCP.2019.0028
·
Oncol Clin Pract 2019;15(4):231-236.

open access

Vol 15, No 4 (2019)
CASE REPORT
Published online: 2019-08-21

Abstract

Hodgkin’s lymphoma (HL) is a neoplastic disease of the lymphoid tissue. It is characterised by the presence of B lymphocyte-derived monoclonal Reed-Sternberg and Hodgkin cells, which tend to create a massive inflammation reaction in lymph nodes. Lymphadenopathy is common. The prognosis depends on the clinical stage according to Ann Arbor (Cotswold’s modification) classification and unfavourable prognostic factors. The ABVD chemotherapy regimen is the gold standard of treatment for patients with HL. This case report presents a patient diagnosed and treated for neck presentation of Hodgkin’s lymphoma intricate sepsis and coxarthritis because of Staphylococcus aureus infection. The treatment was arthrotomy. After the patient’s recovery chemotherapy was continued and complete remission was achieved.

Abstract

Hodgkin’s lymphoma (HL) is a neoplastic disease of the lymphoid tissue. It is characterised by the presence of B lymphocyte-derived monoclonal Reed-Sternberg and Hodgkin cells, which tend to create a massive inflammation reaction in lymph nodes. Lymphadenopathy is common. The prognosis depends on the clinical stage according to Ann Arbor (Cotswold’s modification) classification and unfavourable prognostic factors. The ABVD chemotherapy regimen is the gold standard of treatment for patients with HL. This case report presents a patient diagnosed and treated for neck presentation of Hodgkin’s lymphoma intricate sepsis and coxarthritis because of Staphylococcus aureus infection. The treatment was arthrotomy. After the patient’s recovery chemotherapy was continued and complete remission was achieved.

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Keywords

Hodgkin disease; hip joint; Staphylococcus aureus

About this article
Title

Hodgkin’s lymphoma with multifocal Staphylococcus aureus infection in a 29-year-old male — a case study

Journal

Oncology in Clinical Practice

Issue

Vol 15, No 4 (2019)

Article type

Case report

Pages

231-236

Published online

2019-08-21

DOI

10.5603/OCP.2019.0028

Bibliographic record

Oncol Clin Pract 2019;15(4):231-236.

Keywords

Hodgkin disease
hip joint
Staphylococcus aureus

Authors

Katarzyna Kryszczyszyn-Musialik
Grzegorz Słomian
Krzysztof Musialik

References (30)
  1. Eichenauer DA, Engert A, Dreyling M, et al. ESMO Guidelines Working Group. Hodgkin's lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2011; 22 Suppl 6: vi55–vi58.
  2. Wróbel T. Chłoniak Hodgkina. In: Krzakowski M, Warzocha K (eds). Zalecenia postępowania diagnostyczno-terapeutycznego w nowotworach złośliwych 2013 r. Via Medica, Gdańsk 2013, 981–990.
  3. Wojciechowska U, Didkowska J. Zachorowania i zgony na nowotwory złośliwe w Polsce. Krajowy Rejestr Nowotworów, Centrum Onkologii — Instytut im. Marii Skłodowskiej-Curie. http://onkologia.org.pl/chloniak-hodgkina-c81/.
  4. Meder J. Chłoniak Hodgkina. In: Krzakowski M, Jędrzejczak WW, Kowalczyk JR. et al. (eds). Zalecenia postępowania diagnostyczno-terapeutycznego w nowotworach złośliwych 2011 r. Via Medica, Gdańskr. 2012: 704–716.
  5. Hasenclever D, Diehl V, Armitage J, et al. A Prognostic Score for Advanced Hodgkin's Disease. New England Journal of Medicine. 1998; 339(21): 1506–1514.
  6. National Comprehensive Cancer Network. Hodgkin lymphoma (verson2.2014). hpttp://www.nccn.org/professionals/physicians_gls/pdf/hodgkins.pdf.
  7. Górecki A, Marczyński W, Babiak I. Zasady profilaktyki, rozpoznawania i leczenia nieswoistych zakażeń kości i stawów. Ortop Traumatol Rehabilit. 2008; 4(6); 10: 396415.
  8. Babiak I, Kowalewski M, Szczęsny G, et al. Zapalenia kości i stawów — charakterystyka u dzieci i dorosłych. Zakażenia. 2004; 6.
  9. Vukasinović Z, Spasovski D, Cobeljić G, et al. Septic arthritis of the hip in infancy — diagnostic and therapeutic possibilities. Srp Arh Celok Lek. 2006; 134(1–2): 77–81.
  10. Karimi S, Mohammadi F, Pejhan S, et al. An unusual presentation of Hodkin's lymphoma as a chest wall abscess in association with old tuberculosis. Tanafoss. 2007; 6: 71–74.
  11. Zaman A, Bramley PN, Wyatt J, et al. Hodgkin's disease presenting as liver abscesses. Gut. 1991; 32(8): 959–962.
  12. Pickerill RG, Kaplan PD, Shively JG, et al. Hodgkin's lymphoma presenting as lung abscess. Pa Med. 1987; 90(11): 64–65.
  13. Bloom RA, Freund U, Perkes EH, et al. Acute Hodgkin disease masquerading as splenic abscess. J Surg Oncol. 1981; 17(3): 279–282.
  14. Telfah MM. Hodgkin's lymphoma presents as an inguinal abscess: a case report and literature review. BMJ Case Rep. 2012; 2012.
  15. Pawłowski W, Dorobisz T. Katastrofa terapeutyczna jako następstwo trudności diagnostycznych u 52-letniego pacjenta leczonego z powodu ropnia trzustki. Pol Merkur Lekarski, 2015; XXXIX. ; 232: 231–233.
  16. Shodell M, Kempin S, Siegal FP. Plasmacytoid dendritic cell and CD4 + T cell deficiencies in untreated Hodgkin disease: implications for susceptibility to opportunistic infections. Leuk Lymphoma. 2014; 55(11): 2656–2657.
  17. Simpson JF. Listeria monocytogenes meningitis: an opportunistic infection. J Neurol Neurosurg Psychiatry. 1971; 34(6): 657–663.
  18. Diddie KR, Schanzlin DJ, Mausolf FA, et al. Necrotizing retinitis caused by opportunistic virus infection in a patient with Hodgkin's disease. Am J Ophthalmol. 1979; 88(4): 668–673.
  19. Notter DT, Grossman PL, Rosenberg SA, et al. Infections in patients with Hodgkin's disease: a clinical study of 300 consecutive adult patients. Rev Infect Dis. 1980; 2(5): 761–800.
  20. Newton R, Crouch S, Ansell P, et al. Hodgkin's lymphoma and infection: findings from a UK case-control study. Br J Cancer. 2007; 97(9): 1310–1314.
  21. de Armas Y, Capó V, González I, et al. Concomitant Mycobacterium avium infection and Hodgkin's disease in a lymph node from an HIV-negative child. Pathol Oncol Res. 2011; 17(1): 139–140.
  22. Kumar R, Daga MK, Kamble NL, et al. Rare association of Visceral leishmaniasis with Hodgkin's disease: A case report. Infect Agent Cancer. 2011; 6(1): 17.
  23. Hayes TG, Gill EP, Swarna U. Osteomyelitis of the wrist in a patient with Hodgkin's disease. J Intern Med. 1991; 229(5): 467–469.
  24. Wald ER. Risk factors for osteomyelitis. Am J Med. 1985; 78(6B): 206–212.
  25. Rusu RA, Sîrbu D, Curşeu D, et al. Chemotherapy-related infectious complications in patients with Hematologic malignancies. J Res Med Sci. 2018; 23: 68.
  26. Razak M, Nasiruddin J. An epidemiological study of septic arthritis in Kuala Lumpur Hospital. Med J Malaysia. 1998; 53 Suppl A: 86–94.
  27. De Souza HM, Helito CP, Oliva GB, et al. Clinical and epidemiological characteristics of septic arthritis of the hip, 2006 to 2012, a seven-year review. Clinics (Sao Paulo). 2014; 69(7): 464–468.
  28. Cierny G, Mader JT. Approach to adult osteomyelitis. Orthop Rev. 1987; 16(4): 259–270.
  29. Waldvogel FA, Medoff G, Swartz MN. Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects. N Engl J Med. 1970; 282(4): 198–206.
  30. Karlinj M. Osteornyelitis in children. Cliri Pedintr Med Surg. 1987; 4: 37–56.

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