open access

Vol 12, No 3 (2016)
Case report
Published online: 2016-08-31
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Role of immunohistochemical analysis in the diagnosis of gastric carcinosarcoma, a rare tumour — case report

Shafaq Maqsood
Oncol Clin Pract 2016;12(3):105-107.

open access

Vol 12, No 3 (2016)
CASE REPORT
Published online: 2016-08-31

Abstract

Carcinosarcoma is a malignant tumour that has carcinomatous and sarcomatous components occurring rarely in the stomach with only a handful of case reports, mainly from Japan. We report a case of carcinosarcoma in a fifty-two-year-old female with clinical and histopathological features. The patient underwent complete workup followed by surgical resection. Macroscopically, the tumour was large and ulcerating. Microscopically, it was a carcinosarcoma with myogenic differentiation. Immunohistochemical analysis was done, which led to the diagnosis of gastric carcinosarcoma.
Carcinosarcoma can mimic an adenocarcinoma clinically, and making a diagnosis on the basis of endoscopy or radiology alone is not possible. Our case report highlights the importance of immunohistochemical analysis in the diagnosis of gastric carcinosarcoma.

Abstract

Carcinosarcoma is a malignant tumour that has carcinomatous and sarcomatous components occurring rarely in the stomach with only a handful of case reports, mainly from Japan. We report a case of carcinosarcoma in a fifty-two-year-old female with clinical and histopathological features. The patient underwent complete workup followed by surgical resection. Macroscopically, the tumour was large and ulcerating. Microscopically, it was a carcinosarcoma with myogenic differentiation. Immunohistochemical analysis was done, which led to the diagnosis of gastric carcinosarcoma.
Carcinosarcoma can mimic an adenocarcinoma clinically, and making a diagnosis on the basis of endoscopy or radiology alone is not possible. Our case report highlights the importance of immunohistochemical analysis in the diagnosis of gastric carcinosarcoma.

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Keywords

carcinosarcoma, gastric, pathology, immunohistochemistry

About this article
Title

Role of immunohistochemical analysis in the diagnosis of gastric carcinosarcoma, a rare tumour — case report

Journal

Oncology in Clinical Practice

Issue

Vol 12, No 3 (2016)

Article type

Case report

Pages

105-107

Published online

2016-08-31

Bibliographic record

Oncol Clin Pract 2016;12(3):105-107.

Keywords

carcinosarcoma
gastric
pathology
immunohistochemistry

Authors

Shafaq Maqsood

References (7)
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  4. Cho KJ, Myong NH, Choi DW, et al. Carcinosarcoma of the stomach. A case report with light microscopic, immunohistochemical, and electron microscopic study. APMIS. 1990; 98(11): 991–995.
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  6. Gohongi T, Iida H, Gunji N, et al. Postsurgical radiation therapy for gastric carcinosarcoma with c-kit expression: a case report. World J Gastroenterol. 2015; 21(9): 2830–2835.
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