open access
New simple and low-cost methods for periodic checks of Cyclone® Plus Storage Phosphor System
open access
Abstract
The recent large use of the Cyclone® Plus Storage Phosphor System, especially in European countries, as imaging system for quantification of radiochemical purity of radiopharmaceuticals raised the problem of setting the periodic controls as required by European Legislation. We described simple, low-cost methods for Cyclone® Plus quality controls, which can be useful to evaluate the performance measurement of this imaging system.
Abstract
The recent large use of the Cyclone® Plus Storage Phosphor System, especially in European countries, as imaging system for quantification of radiochemical purity of radiopharmaceuticals raised the problem of setting the periodic controls as required by European Legislation. We described simple, low-cost methods for Cyclone® Plus quality controls, which can be useful to evaluate the performance measurement of this imaging system.
Keywords
Cyclone® Plus Storage Phosphor System, Quality Control, Background, Uniformity, Linearity, Repeatability, radiochemical purity
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About this articleTitle
New simple and low-cost methods for periodic checks of Cyclone® Plus Storage Phosphor System
Journal
Issue
Article type
Research paper
Pages
15-17
Published online
2017-01-04
Page views
1016
Article views/downloads
992
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2017;20(1):15-17.
Keywords
Cyclone® Plus Storage Phosphor System
Quality Control
Background
Uniformity
Linearity
Repeatability
radiochemical purity
Authors
Elisabetta Edalucci
Anna Margherita Maffione
Maria Rosa Fornasier
Mario De Denaro
Giovanni Scian
Franca Dore
Domenico Rubello
References (5)- EudraLex Volume 1 — Pharmaceutical Legislation Medicinal Products for Human Use. http://ec.europa.eu/health/documents/eudralex/index_en.htm (2016.04.27).
- EudraLex Volume 4, Annex 3 — EU Guidelines to Good Manufacturing Practice Medical Products for Human and Veterinary Use. http://ec.europa.eu/health/documents/eudralex/vol-4/ (2016.04.27).
- Guidelines on current good radiopharmacy practice (cGRPP) in the preparation of radiopharmaceuticals, cGRPP guidelines, version 2 March 2007, EANM Radiopharmacy Committee. http://www.eanm.org/publications/guidelines/gl_radioph_cgrpp.pdf (2016.10.22).
- Elsinga P, Todde S, Penuelas I, et al. Radiopharmacy Committee of the EANM. Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals. Eur J Nucl Med Mol Imaging. 2010; 37(5): 1049–1062.
- Cyclone® Plus Storage Phosphor System — Instruction Manual Perkin Elmer Life and Analytical Sciences. https://shop.perkinelmer.com/Content/Images/2006/SFDC/AIMN/Cyclone_Plus.pdf (2016.04.27).
