open access

Vol 22, No 2 (2019)
Clinical vignette
Published online: 2019-07-31
Submitted: 2019-02-04
Accepted: 2019-04-10
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Radiotherapy for breast cancer induced long-term diminished accumulation of radiotracer on bone scan of the irradiated ribs

Andreas Fotopoulos, Chrissa Sioka, Konstantinos Papadimitropoulos, Tzihad Al Boucharali, John Kalef Ezra
DOI: 10.5603/NMR.2019.0020
·
Pubmed: 31482562
·
Nucl. Med. Rev 2019;22(2):85-87.

open access

Vol 22, No 2 (2019)
Clinical vignette
Published online: 2019-07-31
Submitted: 2019-02-04
Accepted: 2019-04-10

Abstract

Radiotherapy may result in long term effects and composition alterations in bones. Bone scintigraphy after radiotherapy may demonstrate decreased skeletal uptake; however, this is a transient effect with bone scan normalized after a few years. We describe a case of a 31-year-old female patient treated for left breast cancer with chemotherapy and radiotherapy, exhibiting reduced and diffuse diphosphonate uptake in the heavily irradiated sections of left ribs, even twelve years post-treatment. Similarly, quantitative computed tomography indicated altered bone composition. To our knowledge this is the first case describing such a long radiation side effect in breast cancer treatment.

Abstract

Radiotherapy may result in long term effects and composition alterations in bones. Bone scintigraphy after radiotherapy may demonstrate decreased skeletal uptake; however, this is a transient effect with bone scan normalized after a few years. We describe a case of a 31-year-old female patient treated for left breast cancer with chemotherapy and radiotherapy, exhibiting reduced and diffuse diphosphonate uptake in the heavily irradiated sections of left ribs, even twelve years post-treatment. Similarly, quantitative computed tomography indicated altered bone composition. To our knowledge this is the first case describing such a long radiation side effect in breast cancer treatment.

Get Citation

Keywords

Radiation therapy; breast cancer; bone scan; radiological imaging; computer tomography; whole body BMD

About this article
Title

Radiotherapy for breast cancer induced long-term diminished accumulation of radiotracer on bone scan of the irradiated ribs

Journal

Nuclear Medicine Review

Issue

Vol 22, No 2 (2019)

Pages

85-87

Published online

2019-07-31

DOI

10.5603/NMR.2019.0020

Pubmed

31482562

Bibliographic record

Nucl. Med. Rev 2019;22(2):85-87.

Keywords

Radiation therapy
breast cancer
bone scan
radiological imaging
computer tomography
whole body BMD

Authors

Andreas Fotopoulos
Chrissa Sioka
Konstantinos Papadimitropoulos
Tzihad Al Boucharali
John Kalef Ezra

References (10)
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