open access
99mTc-Vitamin C SPECT/CT imaging in SARS-CoV-2 associated pneumonia
- Cerrahpasa Medical Faculty, Department of Nuclear Medicine, Istanbul University-Cerrahpasa, Istanbul,Turkey
- The IMC Lab, New York, United States
- Departament of Radiology, Memorial Sloan Kettering Cancer Center, New York, United States
open access
Abstract
We present the first 99mTc-Vitamin C single-photon emission computed tomography/computed tomography (SPECT/CT) images obtained in patients with SARS-CoV-2 (COVID-19) infection. The CT portion of SPECT/CT images showed mostly peripheral patchy and ground-glass opacities in both lungs, which are consistent with a diagnosis of SARS-CoV-2–associated pneumonia in both patients. 99mTc-Vitamin C SPECT images showed increased tracer uptake corresponding to abnormal lung findings seen on CT in patient 1 who was newly diagnosed and treatment naïve. However, no abnormal uptake corresponding to lung CT findings was seen in patient 2 who received anti-SARS-CoV-2 treatment.
Abstract
We present the first 99mTc-Vitamin C single-photon emission computed tomography/computed tomography (SPECT/CT) images obtained in patients with SARS-CoV-2 (COVID-19) infection. The CT portion of SPECT/CT images showed mostly peripheral patchy and ground-glass opacities in both lungs, which are consistent with a diagnosis of SARS-CoV-2–associated pneumonia in both patients. 99mTc-Vitamin C SPECT images showed increased tracer uptake corresponding to abnormal lung findings seen on CT in patient 1 who was newly diagnosed and treatment naïve. However, no abnormal uptake corresponding to lung CT findings was seen in patient 2 who received anti-SARS-CoV-2 treatment.
Keywords
99mTc-Vitamin C; SPECT/CT; SARS-Cov-2, pneumonia
Title
99mTc-Vitamin C SPECT/CT imaging in SARS-CoV-2 associated pneumonia
Journal
Issue
Article type
Clinical vignette
Pages
127-128
Published online
2022-06-09
Page views
4226
Article views/downloads
435
DOI
Pubmed
Bibliographic record
Nucl. Med. Rev 2022;25(2):127-128.
Keywords
99mTc-Vitamin C
SPECT/CT
SARS-Cov-2
pneumonia
Authors
Haluk B. Sayman
Kubra N. Toplutas
James Tunick
Omer Aras
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