open access

Vol 19, No 1 (2016)
Case Report
Published online: 2016-01-29
Submitted: 2015-08-07
Accepted: 2015-12-30
Get Citation

Parathyroid cancer — difficult diagnosis — a case report

Aleksandra Joanna Pyzik, Beata Matyjaszek-Matuszek, Agnieszka Zwolak, Beata Chrapko, Dawid Pyzik, Katarzyna Strawa- Zakościelna
DOI: 10.5603/NMR.2016.0009
·
Pubmed: 26838944
·
Nucl. Med. Rev 2016;19(1):46-50.

open access

Vol 19, No 1 (2016)
Case Report
Published online: 2016-01-29
Submitted: 2015-08-07
Accepted: 2015-12-30

Abstract

Parathyroid cancer is a rare disorder of unclear etiology that is difficult to diagnose and treat. It is most often diagnosed incidentally based on multi-organ non-specific symptoms of hypercalcemia as a consequence of parathyroid hormone oversecretion. We present a case of a male with primary hyperparathyroidism who was diagnosed with parathyroid cancer ectopically located in the mediastinum only after the third surgery. However, due to chronic hypercalcemia, problems with localization and a bad clinical condition, the patient was not able to undergo a radical resection and one year after the first pathological fracture died. Taking into consideration the whole clinical picture we want to emphasize the need to apply comprehensive differential diagnosis of hypercalcemia and localization diagnosis of parathyroid tissue with a use of MIBI scintigraphy accompanied by the computed tomography and magnetic resonance imaging, as the most specific diagnostic tools employed in this pathology.

Abstract

Parathyroid cancer is a rare disorder of unclear etiology that is difficult to diagnose and treat. It is most often diagnosed incidentally based on multi-organ non-specific symptoms of hypercalcemia as a consequence of parathyroid hormone oversecretion. We present a case of a male with primary hyperparathyroidism who was diagnosed with parathyroid cancer ectopically located in the mediastinum only after the third surgery. However, due to chronic hypercalcemia, problems with localization and a bad clinical condition, the patient was not able to undergo a radical resection and one year after the first pathological fracture died. Taking into consideration the whole clinical picture we want to emphasize the need to apply comprehensive differential diagnosis of hypercalcemia and localization diagnosis of parathyroid tissue with a use of MIBI scintigraphy accompanied by the computed tomography and magnetic resonance imaging, as the most specific diagnostic tools employed in this pathology.

Get Citation

Keywords

hyperparathyroidism, parathyroid cancer, MIBI scintigraphy, MRI, CT

About this article
Title

Parathyroid cancer — difficult diagnosis — a case report

Journal

Nuclear Medicine Review

Issue

Vol 19, No 1 (2016)

Pages

46-50

Published online

2016-01-29

DOI

10.5603/NMR.2016.0009

Pubmed

26838944

Bibliographic record

Nucl. Med. Rev 2016;19(1):46-50.

Keywords

hyperparathyroidism
parathyroid cancer
MIBI scintigraphy
MRI
CT

Authors

Aleksandra Joanna Pyzik
Beata Matyjaszek-Matuszek
Agnieszka Zwolak
Beata Chrapko
Dawid Pyzik
Katarzyna Strawa- Zakościelna

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., Świętokrzyska 73 street, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl