open access

Vol 18, No 2 (2015)
Case Report
Published online: 2015-07-31
Submitted: 2015-07-31
Accepted: 2015-07-31
Get Citation

99mTc(V)-DMSA SPECT-CT findings in a case of Gorham-Stout disease

Victor M. Alves, Tiago S. Vieira, Nelson S. Amorim, Ana Oliveira, André Rodrigues, Jorge G. Pereira
DOI: 10.5603/NMR.2015.0023
·
Pubmed: 26315871
·
Nucl. Med. Rev 2015;18(2):97-101.

open access

Vol 18, No 2 (2015)
Case Report
Published online: 2015-07-31
Submitted: 2015-07-31
Accepted: 2015-07-31

Abstract

The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.

Abstract

The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.

Get Citation

Keywords

99mTc(V)-dimercaptosuccinic acid, bone scintigraphy, Gorham-Stout disease, single-photon emission computed tomography/computed tomography

About this article
Title

99mTc(V)-DMSA SPECT-CT findings in a case of Gorham-Stout disease

Journal

Nuclear Medicine Review

Issue

Vol 18, No 2 (2015)

Pages

97-101

Published online

2015-07-31

DOI

10.5603/NMR.2015.0023

Pubmed

26315871

Bibliographic record

Nucl. Med. Rev 2015;18(2):97-101.

Keywords

99mTc(V)-dimercaptosuccinic acid
bone scintigraphy
Gorham-Stout disease
single-photon emission computed tomography/computed tomography

Authors

Victor M. Alves
Tiago S. Vieira
Nelson S. Amorim
Ana Oliveira
André Rodrigues
Jorge G. Pereira

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