open access

Vol 19, No 1 (2016)
Original articles
Published online: 2016-01-29
Submitted: 2015-04-20
Accepted: 2015-11-10
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Comparison of planar DMSA scan with an evaluation based on SPECT imaging in the split renal function assessment

Daniela Chroustová, Jirí Trnka, Veřa Šírová, Ivana Urbanova, Jan Langer, Jozef Kubinyi
DOI: 10.5603/NMR.2016.0003
·
Pubmed: 26841374
·
Nucl. Med. Rev 2016;19(1):12-17.

open access

Vol 19, No 1 (2016)
Original articles
Published online: 2016-01-29
Submitted: 2015-04-20
Accepted: 2015-11-10

Abstract

BACKGROUND: Validation of the 99mTc-DMSA planar scintigraphy accuracy for split renal function assessment and comparison with evaluation based on SPECT imaging both with and without CT attenuation correction.

MATERIALS AND METHODS: For split renal function assessment two methods were used: A) planar scintigraphy based on anterior and posterior projections using correction for kidney depth calculated by the geometric mean; B) semi-quantitative evaluation based on SPECT (B1) and attenuation-corrected SPECT/CT (B2) images using locally developed software for kidney segmentation and voxel-based analysis. All three methods were performed with a phantom simulating body including pair of kidneys. For patient study methods A and B1 were applied on a group of 140 children and adolescents with various renal diseases. Renal function ratios were compared both mutually and with physically measured activity ratios in the phantom.

RESULTS: Method A provided results which were closest to measured reference values (average absolute difference of 0.9 percentage points [pp]). Method B1 was noticeably worse (2.1pp), whereas attenuation correction (B2) improved tomography results considerably (1.3 pp). The superiority of planar imaging could be caused among others by differences in creation of planar range of interest compared to tomographic volume of interest. However all the differences were under the threshold of any clinical importance. The comparison between method A and B1 based on patient study also showed differences mostly of none clinical importance.

CONCLUSION: Routine evaluation of split renal function using planar technique with correction of the kidney depth is at least equivalent to tomographic evaluation, and there is no need to update the established clinical practice.

Abstract

BACKGROUND: Validation of the 99mTc-DMSA planar scintigraphy accuracy for split renal function assessment and comparison with evaluation based on SPECT imaging both with and without CT attenuation correction.

MATERIALS AND METHODS: For split renal function assessment two methods were used: A) planar scintigraphy based on anterior and posterior projections using correction for kidney depth calculated by the geometric mean; B) semi-quantitative evaluation based on SPECT (B1) and attenuation-corrected SPECT/CT (B2) images using locally developed software for kidney segmentation and voxel-based analysis. All three methods were performed with a phantom simulating body including pair of kidneys. For patient study methods A and B1 were applied on a group of 140 children and adolescents with various renal diseases. Renal function ratios were compared both mutually and with physically measured activity ratios in the phantom.

RESULTS: Method A provided results which were closest to measured reference values (average absolute difference of 0.9 percentage points [pp]). Method B1 was noticeably worse (2.1pp), whereas attenuation correction (B2) improved tomography results considerably (1.3 pp). The superiority of planar imaging could be caused among others by differences in creation of planar range of interest compared to tomographic volume of interest. However all the differences were under the threshold of any clinical importance. The comparison between method A and B1 based on patient study also showed differences mostly of none clinical importance.

CONCLUSION: Routine evaluation of split renal function using planar technique with correction of the kidney depth is at least equivalent to tomographic evaluation, and there is no need to update the established clinical practice.

Get Citation

Keywords

static renal 99mTc-DMSA scintigraphy, 3D SPECT method analysis, split renal function ratio, childhood

About this article
Title

Comparison of planar DMSA scan with an evaluation based on SPECT imaging in the split renal function assessment

Journal

Nuclear Medicine Review

Issue

Vol 19, No 1 (2016)

Pages

12-17

Published online

2016-01-29

DOI

10.5603/NMR.2016.0003

Pubmed

26841374

Bibliographic record

Nucl. Med. Rev 2016;19(1):12-17.

Keywords

static renal 99mTc-DMSA scintigraphy
3D SPECT method analysis
split renal function ratio
childhood

Authors

Daniela Chroustová
Jirí Trnka
Veřa Šírová
Ivana Urbanova
Jan Langer
Jozef Kubinyi

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