18F-FDG-PET/CT in staging, recurrence detection and response evaluation of primary splenic lymphoma with eight years follow up

Abstract

Primary splenic lymphomas (PSL) are rare malignancies which involve spleen with or without splenic hilar lymph nodes. Confirmation of diagnosis depends upon tissue sampling but noninvasive methods are useful in early diagnosis, treatment response monitoring and recurrence detection. Here we describe a case of PSL detected by ¹⁸F-FDG-PET/CT which was histopathologically proven to be diffuse large B-cell lymphoma (DLBCL) treated with CHOP regimen. ¹⁸F-FDG-PET/CT was found to be very useful in all stages (staging, recurrence detection and treatment response monitoring) of PSL with eight years of follow up.