open access

Vol 18, No 1 (2015)
Original articles
Published online: 2015-01-29
Submitted: 2014-03-16
Accepted: 2014-09-18
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Do ejection fraction and other gated stress rest myocardial perfusion parameters differ by age and gender?

Masoud Moslehi, Soudabeh Alidadi, Ehsan Assadollahi, Majid Assadi
DOI: 10.5603/NMR.2015.0003
·
Pubmed: 25633510
·
Nucl. Med. Rev 2015;18(1):7-12.

open access

Vol 18, No 1 (2015)
Original articles
Published online: 2015-01-29
Submitted: 2014-03-16
Accepted: 2014-09-18

Abstract

BACKGROUND: We have studied the end-diastolic volume (EDV), the end-systolic volume (ESV), and the ejection fraction (EF) for patients who had normal results on treadmill exercise tests and perfusion scans. We also studied normal wall motion as diagnosed by gated myocardial perfusion imaging with the quantitative gated single photon emission tomography (QGSPECT) software set to launch a range of normal values. In addition, we evaluated differences based on age and gender.

MATERIALS AND METHODS: All subjects with normal results on Bruce exercise and myocardial perfusion imaging QGSPECT using the 2-days stress-rest technetium-99m (99mTc) sestamibi protocol were enrolled in the study. The quantitated functional data of EDV, ESV, and EF using the QGSPECT software were assessed in the rest and stress studies. The association of quantitated functional data with age and sex at both stress and rest was studied in 78 subjects with no symptoms from the cardiovascular system and normal QGSPECT imaging, 29 males (mean age: 58.41 ± 9.0 years) and 49 females (mean age: 58.18 ± 9.0 years). Also studied were differences between males and females.

RESULTS: Our results showed that in women compared with men only stress EF showed a significantly higher value (P = 0.02), whereas all other parameters including REF, SESV, SEDV, RESV, and REDV did not demonstrate a significant difference between men and women (P value > 0.05).

CONCLUSION: The study showed that EF as determined by the QGSPECT technique should be considered as gender-matched normative parameter.

Abstract

BACKGROUND: We have studied the end-diastolic volume (EDV), the end-systolic volume (ESV), and the ejection fraction (EF) for patients who had normal results on treadmill exercise tests and perfusion scans. We also studied normal wall motion as diagnosed by gated myocardial perfusion imaging with the quantitative gated single photon emission tomography (QGSPECT) software set to launch a range of normal values. In addition, we evaluated differences based on age and gender.

MATERIALS AND METHODS: All subjects with normal results on Bruce exercise and myocardial perfusion imaging QGSPECT using the 2-days stress-rest technetium-99m (99mTc) sestamibi protocol were enrolled in the study. The quantitated functional data of EDV, ESV, and EF using the QGSPECT software were assessed in the rest and stress studies. The association of quantitated functional data with age and sex at both stress and rest was studied in 78 subjects with no symptoms from the cardiovascular system and normal QGSPECT imaging, 29 males (mean age: 58.41 ± 9.0 years) and 49 females (mean age: 58.18 ± 9.0 years). Also studied were differences between males and females.

RESULTS: Our results showed that in women compared with men only stress EF showed a significantly higher value (P = 0.02), whereas all other parameters including REF, SESV, SEDV, RESV, and REDV did not demonstrate a significant difference between men and women (P value > 0.05).

CONCLUSION: The study showed that EF as determined by the QGSPECT technique should be considered as gender-matched normative parameter.
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Keywords

gated SPECT, ejection fraction, end diastolic volume, end systolic volume, myocardial perfusion imaging

About this article
Title

Do ejection fraction and other gated stress rest myocardial perfusion parameters differ by age and gender?

Journal

Nuclear Medicine Review

Issue

Vol 18, No 1 (2015)

Pages

7-12

Published online

2015-01-29

DOI

10.5603/NMR.2015.0003

Pubmed

25633510

Bibliographic record

Nucl. Med. Rev 2015;18(1):7-12.

Keywords

gated SPECT
ejection fraction
end diastolic volume
end systolic volume
myocardial perfusion imaging

Authors

Masoud Moslehi
Soudabeh Alidadi
Ehsan Assadollahi
Majid Assadi

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