open access

Vol 17, No 1 (2014)
Case Report
Published online: 2014-03-03
Submitted: 2013-10-22
Accepted: 2013-11-21
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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) — imaging manifestations of renal involvement

Sina Izadyar, Farhad Samiei, Ali Gholamrezanezhad
DOI: 10.5603/NMR.2014.0011
·
Nucl. Med. Rev 2014;17(1):44-46.

open access

Vol 17, No 1 (2014)
Case Report
Published online: 2014-03-03
Submitted: 2013-10-22
Accepted: 2013-11-21

Abstract

A 23-year-old lady presented with abdominal fullness and distension as well as large abdominal masses in physical exam. Upon ultrasonographic evaluation, two large space occupying lesions anterior to kidneys, with no clear distinction from renal tissue, as well as bilateral hydronephrosis were found. The findings were confirmed by MRI. Histopathological analysis of renal masses and lymph nodes showed proliferation of histiocytes mixed with occasional multinucleated giant cells, immunostaining of which was positive for S-100 and CD68. We present renal scintigraphy features of this rare case of renal sinus histiocytosis with massive intraabdominal lymphadenopathy (Rosai-Dorfman disease).

Abstract

A 23-year-old lady presented with abdominal fullness and distension as well as large abdominal masses in physical exam. Upon ultrasonographic evaluation, two large space occupying lesions anterior to kidneys, with no clear distinction from renal tissue, as well as bilateral hydronephrosis were found. The findings were confirmed by MRI. Histopathological analysis of renal masses and lymph nodes showed proliferation of histiocytes mixed with occasional multinucleated giant cells, immunostaining of which was positive for S-100 and CD68. We present renal scintigraphy features of this rare case of renal sinus histiocytosis with massive intraabdominal lymphadenopathy (Rosai-Dorfman disease).

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Keywords

sinus histiocytosis, massive lymphadenopathy, Rosai-Dorfman disease, renal scintigraphy, 99mTc-DMSA, 99mTc-EC, magnetic resonance imaging

About this article
Title

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) — imaging manifestations of renal involvement

Journal

Nuclear Medicine Review

Issue

Vol 17, No 1 (2014)

Pages

44-46

Published online

2014-03-03

DOI

10.5603/NMR.2014.0011

Bibliographic record

Nucl. Med. Rev 2014;17(1):44-46.

Keywords

sinus histiocytosis
massive lymphadenopathy
Rosai-Dorfman disease
renal scintigraphy
99mTc-DMSA
99mTc-EC
magnetic resonance imaging

Authors

Sina Izadyar
Farhad Samiei
Ali Gholamrezanezhad

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