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Non-FDG PET studies in oncology: bone PET with fluoride (18F)
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Abstract
and monitor bone malignancies. The two main functional modalities
are scintigraphy and PET. PET has superior diagnostic
performance over scintigraphy or SPECT in all indications, with
the exception of some rare studies in mandibular invasion by
squamous cell carcinoma or osteosarcoma. In oncology, it is
not yet clear whether there is an added value of bone PET with
fluoride (18F) to information brought by the detection of cancer
tissue itself by metabolic tracers such as FDG, fluorocholine
(18F), iodine-124, FDOPA (18F) or somatostatin analogues labelled
with gallium-68. This article reviews the results of the
available studies on this topic.
Abstract
and monitor bone malignancies. The two main functional modalities
are scintigraphy and PET. PET has superior diagnostic
performance over scintigraphy or SPECT in all indications, with
the exception of some rare studies in mandibular invasion by
squamous cell carcinoma or osteosarcoma. In oncology, it is
not yet clear whether there is an added value of bone PET with
fluoride (18F) to information brought by the detection of cancer
tissue itself by metabolic tracers such as FDG, fluorocholine
(18F), iodine-124, FDOPA (18F) or somatostatin analogues labelled
with gallium-68. This article reviews the results of the
available studies on this topic.
Keywords
bone PET, bone scintigraphy, fluoride (18F), FDG, fluorocholine (18F), bone metastasis, primary bone tumour, comparative study
Title
Non-FDG PET studies in oncology: bone PET with fluoride (18F)
Journal
Issue
Pages
52-60
Published online
2013-02-19
Page views
488
Article views/downloads
4283
Keywords
bone PET
bone scintigraphy
fluoride (18F)
FDG
fluorocholine (18F)
bone metastasis
primary bone tumour
comparative study
Authors
Sona Balogova
Frédéric Paycha
Lucia Kaliska
Jolanta Kunikowska
Jean-Noël Talbot