open access

Vol 15, Supp. C (2012)
Published online: 2013-02-19
Submitted: 2013-02-25
Accepted: 2013-02-25
Get Citation

Non-FDG PET studies in oncology: bone PET with fluoride (18F)

Sona Balogova, Frédéric Paycha, Lucia Kaliska, Jolanta Kunikowska, Jean-Noël Talbot

open access

Vol 15, Supp. C (2012)
Published online: 2013-02-19
Submitted: 2013-02-25
Accepted: 2013-02-25

Abstract

Various imaging modalities are currently available to diagnose
and monitor bone malignancies. The two main functional modalities
are scintigraphy and PET. PET has superior diagnostic
performance over scintigraphy or SPECT in all indications, with
the exception of some rare studies in mandibular invasion by
squamous cell carcinoma or osteosarcoma. In oncology, it is
not yet clear whether there is an added value of bone PET with
fluoride (18F) to information brought by the detection of cancer
tissue itself by metabolic tracers such as FDG, fluorocholine
(18F), iodine-124, FDOPA (18F) or somatostatin analogues labelled
with gallium-68. This article reviews the results of the
available studies on this topic.

Abstract

Various imaging modalities are currently available to diagnose
and monitor bone malignancies. The two main functional modalities
are scintigraphy and PET. PET has superior diagnostic
performance over scintigraphy or SPECT in all indications, with
the exception of some rare studies in mandibular invasion by
squamous cell carcinoma or osteosarcoma. In oncology, it is
not yet clear whether there is an added value of bone PET with
fluoride (18F) to information brought by the detection of cancer
tissue itself by metabolic tracers such as FDG, fluorocholine
(18F), iodine-124, FDOPA (18F) or somatostatin analogues labelled
with gallium-68. This article reviews the results of the
available studies on this topic.
Get Citation

Keywords

bone PET, bone scintigraphy, fluoride (18F), FDG, fluorocholine (18F), bone metastasis, primary bone tumour, comparative study

About this article
Title

Non-FDG PET studies in oncology: bone PET with fluoride (18F)

Journal

Nuclear Medicine Review

Issue

Vol 15, Supp. C (2012)

Pages

52-60

Published online

2013-02-19

Keywords

bone PET
bone scintigraphy
fluoride (18F)
FDG
fluorocholine (18F)
bone metastasis
primary bone tumour
comparative study

Authors

Sona Balogova
Frédéric Paycha
Lucia Kaliska
Jolanta Kunikowska
Jean-Noël Talbot

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