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Cerebral blood flow SPECT scanning in cortico-basal degeneration
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Abstract
BACKGROUND: Idiopathic Parkinson’s disease accounts for ca. 75% of all cases of Parkinsonism. Corticobasal degeneration is a relatively rare example of the so-called “Parkinson-plus” syndrome.
METHODS AND RESULTS: The authors present the case of a 56-year-old woman with rigidity and atypical tremor of upper extremity followed by gait apraxia, dysarthria, bilateral pyramidal signs and myoclonus. There was no improvement after treatment with L-dopa. The disease has progressed, but the patient is still alive. On the basis of clinical data a diagnosis of corticobasal degeneration has been established. Cerebral blood flow SPECT scanning revealed diffuse hypoperfusion of left frontal lobe, antero-inferior part of the left temporal lobe and left basal ganglia. The case illustrates the usefulness of brain SPECT in atypical forma of Parkinson’s disease.
Abstract
BACKGROUND: Idiopathic Parkinson’s disease accounts for ca. 75% of all cases of Parkinsonism. Corticobasal degeneration is a relatively rare example of the so-called “Parkinson-plus” syndrome.
METHODS AND RESULTS: The authors present the case of a 56-year-old woman with rigidity and atypical tremor of upper extremity followed by gait apraxia, dysarthria, bilateral pyramidal signs and myoclonus. There was no improvement after treatment with L-dopa. The disease has progressed, but the patient is still alive. On the basis of clinical data a diagnosis of corticobasal degeneration has been established. Cerebral blood flow SPECT scanning revealed diffuse hypoperfusion of left frontal lobe, antero-inferior part of the left temporal lobe and left basal ganglia. The case illustrates the usefulness of brain SPECT in atypical forma of Parkinson’s disease.
Title
Cerebral blood flow SPECT scanning in cortico-basal degeneration
Journal
Issue
Pages
85-86
Published online
2000-02-25
Page views
450
Article views/downloads
1430
Bibliographic record
Nucl. Med. Rev 1999;2(2):85-86.
Authors
J. Sławek