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Detection of DCIS using 99mTc-MIBI scintimammography in patients with suspected primary breast cancer, comparison with conventional mammography
open access
Abstract
MATERIAL AND METHODS: This study was performed to determine the possible accuracy of SMM in finding DCIS and comparing this with the accuracy of XMM in the same patient. Over a 3 year period 353 patients with no previous history of breast cancer were imaged with both XMM and SMM. The histology of any suspect area was verified by pathological examination of biopsy material. There were 203 malignant breast tumours.
RESULTS: In those 203 cancers there were 15 pure DCIS cancers. SMM correctly diagnosed 12 of these (sensitivity was 80%). XMM diagnosed correctly 8 DCIS (sensitivity 53%) and was equivocal in 2. Combining of both SMM and XMM provided the best result with all but one DCIS identified (sensitivity 93%).
CONCLUSIONS: This study shows that the SMM is helpful in detecting DCIS in those cases where XMM failed to detect DCIS or was equivocal. The combination of the two techniques produces a higher sensitivity result than either modality alone.
Abstract
MATERIAL AND METHODS: This study was performed to determine the possible accuracy of SMM in finding DCIS and comparing this with the accuracy of XMM in the same patient. Over a 3 year period 353 patients with no previous history of breast cancer were imaged with both XMM and SMM. The histology of any suspect area was verified by pathological examination of biopsy material. There were 203 malignant breast tumours.
RESULTS: In those 203 cancers there were 15 pure DCIS cancers. SMM correctly diagnosed 12 of these (sensitivity was 80%). XMM diagnosed correctly 8 DCIS (sensitivity 53%) and was equivocal in 2. Combining of both SMM and XMM provided the best result with all but one DCIS identified (sensitivity 93%).
CONCLUSIONS: This study shows that the SMM is helpful in detecting DCIS in those cases where XMM failed to detect DCIS or was equivocal. The combination of the two techniques produces a higher sensitivity result than either modality alone.
Keywords
breast imaging; DCIS; scintimammography
Title
Detection of DCIS using 99mTc-MIBI scintimammography in patients with suspected primary breast cancer, comparison with conventional mammography
Journal
Issue
Pages
41-45
Published online
2000-02-25
Page views
587
Article views/downloads
1163
Bibliographic record
Nucl. Med. Rev 2000;3(1):41-45.
Keywords
breast imaging
DCIS
scintimammography
Authors
Jarosław B. Ćwikła
John R. Buscombe
Andrew J.W. Hilson