open access

Vol 3, No 1 (2000)
Published online: 2000-02-25
Submitted: 2012-01-23
Get Citation

Diagnostic value of 99mTc-HM-PAO leukocyte scintigraphy and computer tomography in patients with sternal wound infections

Miklós Papós, Ildikó Nehéz, Imre Simonfalvi, Gábor Kovács, László Csernay, László Pávics
Nucl. Med. Rev 2000;3(1):35-39.

open access

Vol 3, No 1 (2000)
Published online: 2000-02-25
Submitted: 2012-01-23

Abstract

METHODS: 99mTc-HM-PAO leukocyte scintigraphy (LS) and computer tomography (CT) were carried out on 19 patients after cardiac surgery; 10 patients with a high clinical probability of an infected sternal wound (group II) and additionally 9 postoperative patients without clinical symptoms of infection, as a control group (group I). LS was carried out with mixed, autologous leukocytes, labelled with 99mTc-HM-PAO in vitro. CT scans were obtained with the use of intravenous contrast material. Findings from the LS of control patients (group I) were as follows: a cold area in the view of the sternum, a 'biffed sternum' and a diffuse, increased lung uptake of leukocytes. The CT scans of the control group showed focal oedema, focal haematoma and moderate sternal abnormalities. The CT findings of a well-defined fluid collection in the retrosternal space led to one control patient being classified as having a retrosternal abscess. In the group II, the LS finding of an increased leukocyte uptake and the CT finding of a structural irregularity of the sternum, or of air or fluid collection in the retrosternal space, were taken as signs of infection. In 11 of the 13 cases, the infection was verified clinically: 9 of these proved positive on LS and 8 on CT. LS was positive in cases with either superficial or deep processes. In all cases, CT revealed whether the infection was limited to the presternal space or whether the sternum and mediastinum were also involved.
CONCLUSIONS: LS and CT are sensitive methods for the early detection of postoperative sternal wound infections. CT is superior for the exact localisation of the process, while specific signs of infection can be differentiated from those of uninfected sternotomy by the use of LS. A combination of LS and CT is suggested in the diagnosis of poststernotomy infection.

Abstract

METHODS: 99mTc-HM-PAO leukocyte scintigraphy (LS) and computer tomography (CT) were carried out on 19 patients after cardiac surgery; 10 patients with a high clinical probability of an infected sternal wound (group II) and additionally 9 postoperative patients without clinical symptoms of infection, as a control group (group I). LS was carried out with mixed, autologous leukocytes, labelled with 99mTc-HM-PAO in vitro. CT scans were obtained with the use of intravenous contrast material. Findings from the LS of control patients (group I) were as follows: a cold area in the view of the sternum, a 'biffed sternum' and a diffuse, increased lung uptake of leukocytes. The CT scans of the control group showed focal oedema, focal haematoma and moderate sternal abnormalities. The CT findings of a well-defined fluid collection in the retrosternal space led to one control patient being classified as having a retrosternal abscess. In the group II, the LS finding of an increased leukocyte uptake and the CT finding of a structural irregularity of the sternum, or of air or fluid collection in the retrosternal space, were taken as signs of infection. In 11 of the 13 cases, the infection was verified clinically: 9 of these proved positive on LS and 8 on CT. LS was positive in cases with either superficial or deep processes. In all cases, CT revealed whether the infection was limited to the presternal space or whether the sternum and mediastinum were also involved.
CONCLUSIONS: LS and CT are sensitive methods for the early detection of postoperative sternal wound infections. CT is superior for the exact localisation of the process, while specific signs of infection can be differentiated from those of uninfected sternotomy by the use of LS. A combination of LS and CT is suggested in the diagnosis of poststernotomy infection.
Get Citation

Keywords

sternotomy; wound infection; 99mTc-HM-PAO leukocyte scintigraphy; CT

About this article
Title

Diagnostic value of 99mTc-HM-PAO leukocyte scintigraphy and computer tomography in patients with sternal wound infections

Journal

Nuclear Medicine Review

Issue

Vol 3, No 1 (2000)

Pages

35-39

Published online

2000-02-25

Bibliographic record

Nucl. Med. Rev 2000;3(1):35-39.

Keywords

sternotomy
wound infection
99mTc-HM-PAO leukocyte scintigraphy
CT

Authors

Miklós Papós
Ildikó Nehéz
Imre Simonfalvi
Gábor Kovács
László Csernay
László Pávics

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., Świętokrzyska 73 street, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl