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Vol 5, No 1 (2002)
Submitted: 2012-01-23
Published online: 2002-01-17
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Comparative diagnostic value of the breath test and the urine test with 14C-urea in the detection of the Helicobacter pylori infection

Zbigniew Kopański, Aleksandra Jung, Marta Wasilewska-Radwańska, Tadeusz Kuc, Małgorzata Schlegel-Zawadzka, Bożena Witkowska
Nucl. Med. Rev 2002;5(1):21-24.

open access

Vol 5, No 1 (2002)
Submitted: 2012-01-23
Published online: 2002-01-17

Abstract

Among 92 patients with chronic gastritis we conducted a synchronous diagnosis of the Helicobacter pylori (H. pylori) infection using a culture and a serological test (IFP), in conjunction with breath and urine tests involving 14C-urea (BTU-C14 and UTU-C14). The infection was confirmed by isolation in 71 persons (77.2%), the presence of specific IgG in the blood serum was found in 75 (81.5%). In comparison, the BTU-C14 indicated a group of 77 people (83.7%) as infected, and the UTU-C14 a group of 76 (82.6%). In order to determine the diagnostic value (sensitivity, specificity and efficiency) of the latter tests, the results were compared with those of the culture and of the serological tests. It was found that the BTU-C14 test used showed a 100% sensitivity, a 89.5% specificity and a 97.9% efficiency. The UTU-C14 test showed a 100.0% sensitivity, a 94.4% specificity and a 98.9% efficiency in the detection of the H. pylori infection.

Abstract

Among 92 patients with chronic gastritis we conducted a synchronous diagnosis of the Helicobacter pylori (H. pylori) infection using a culture and a serological test (IFP), in conjunction with breath and urine tests involving 14C-urea (BTU-C14 and UTU-C14). The infection was confirmed by isolation in 71 persons (77.2%), the presence of specific IgG in the blood serum was found in 75 (81.5%). In comparison, the BTU-C14 indicated a group of 77 people (83.7%) as infected, and the UTU-C14 a group of 76 (82.6%). In order to determine the diagnostic value (sensitivity, specificity and efficiency) of the latter tests, the results were compared with those of the culture and of the serological tests. It was found that the BTU-C14 test used showed a 100% sensitivity, a 89.5% specificity and a 97.9% efficiency. The UTU-C14 test showed a 100.0% sensitivity, a 94.4% specificity and a 98.9% efficiency in the detection of the H. pylori infection.

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Keywords

Helicobacter pylori; breath test with 14C-urea; urine test with 14C-urea; chronic gastritis

About this article
Title

Comparative diagnostic value of the breath test and the urine test with 14C-urea in the detection of the Helicobacter pylori infection

Journal

Nuclear Medicine Review

Issue

Vol 5, No 1 (2002)

Pages

21-24

Published online

2002-01-17

Page views

677

Article views/downloads

1278

Bibliographic record

Nucl. Med. Rev 2002;5(1):21-24.

Keywords

Helicobacter pylori
breath test with 14C-urea
urine test with 14C-urea
chronic gastritis

Authors

Zbigniew Kopański
Aleksandra Jung
Marta Wasilewska-Radwańska
Tadeusz Kuc
Małgorzata Schlegel-Zawadzka
Bożena Witkowska

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