Vol 27 (2024): Continuous Publishing
Guidelines / Expert consensus
Published online: 2024-11-25
Current state and prospects for the development of nuclear medicine in Poland
DOI: 10.5603/nmr.102810
Nucl. Med. Rev 2024;27:42-52.
Abstract
The aim of the report is to present the current state of equipment, radiopharmacy, dosimetry, and selected clinical applications, together with proposed new solutions and expected directions of development of classic nuclear medicine and positron emission tomography (PET). The statement presents the individual points of view of the members of the Commission for Nuclear Medicine of the Committee of Medical Physics, Radiobiology and Diagnostic Imaging of the Polish Academy of Sciences in the 2020–2023 term.
Keywords: single photon emission tomography/computed tomographypositron emission tomography/ /computed tomographyscintigraphyradioisotope therapyradiopharmacytherapeutic dosimetry
References
- Kunikowska J, Królicki L, Czepczyński R. Nuclear imaging and therapy in oncology in Poland in 2021–2022. Eur J Nucl Med Mol Imaging. 2023; 50(8): 2236–2239.
- Akamatsu Go, Tsutsui Y, Daisaki H, et al. A review of harmonization strategies for quantitative PET. Ann Nucl Med. 2023; 37(2): 71–88.
- Aide N, Lasnon C, Veit-Haibach P, et al. EANM/EARL harmonization strategies in PET quantification: from daily practice to multicentre oncological studies. Eur J Nucl Med Mol Imaging. 2017; 44(Suppl 1): 17–31.
- Dziennik Urzędowy Ministra Zdrowia. https://www.gov.pl/ (26.09.2024).
- Rejestry e-zdrowie. https://rejestry.ezdrowie.gov.pl/rpl/search/public (26.09.2024).
- Gillings N, Hjelstuen O, Ballinger J, et al. Guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals. EJNMMI Radiopharm Chem. 2021; 6(1): 8.
- Kunikowska J, Zemczak A, Kołodziej M, et al. Tandem peptide receptor radionuclide therapy using Y/Lu-DOTATATE for neuroendocrine tumors efficacy and side-effects - polish multicenter experience. Eur J Nucl Med Mol Imaging. 2020; 47(4): 922–933.
- Hubalewska-Dydejczyk A, Fröss-Baron K, Mikołajczak R, et al. 99mTc-EDDA/HYNIC-octreotate scintigraphy, an efficient method for the detection and staging of carcinoid tumours: results of 3 years' experience. Eur J Nucl Med Mol Imaging. 2006; 33(10): 1123–1133.
- Sowa-Staszczak A, Pach D, Mikołajczak R, et al. Glucagon-like peptide-1 receptor imaging with [Lys40(Ahx-HYNIC- 99mTc/EDDA)NH2]-exendin-4 for the detection of insulinoma. Eur J Nucl Med Mol Imaging. 2013; 40(4): 524–531.
- Lezaic L, Erba PA, Decristoforo C, et al. [In]In-CP04 as a novel cholecystokinin-2 receptor ligand with theranostic potential in patients with progressive or metastatic medullary thyroid cancer: final results of a GRAN-T-MTC Phase I clinical trial. Eur J Nucl Med Mol Imaging. 2023; 50(3): 892–907.
- Opalinska M, Lezaic L, Decristoforo C, et al. Comparison of 99mTc radiolabeled somatostatin antagonist with [ Ga]Ga-DOTA-TATE in a patient with advanced neuroendocrine tumor. Eur J Nucl Med Mol Imaging. 2023; 50(13): 4110–4111.
- Petranović Ovčariček P, Giovanella L, Carrió Gasset I, et al. The EANM practice guidelines for parathyroid imaging. Eur J Nucl Med Mol Imaging. 2021; 48(9): 2801–2822.
- Ricciato MP, Di Donna V, Perotti G, et al. The role of adrenal scintigraphy in the diagnosis of subclinical Cushing's syndrome and the prediction of post-surgical hypoadrenalism. World J Surg. 2014; 38(6): 1328–1335.
- Powlson AS, Gurnell M, Brown MJ. Nuclear imaging in the diagnosis of primary aldosteronism. Curr Opin Endocrinol Diabetes Obes. 2015; 22(3): 150–156.
- Koffas A, Giakoustidis A, Papaefthymiou A, et al. Diagnostic work-up and advancement in the diagnosis of gastroenteropancreatic neuroendocrine neoplasms. Front Surg. 2023; 10: 1064145.
- Mikołajczak R, Maecke HR. Radiopharmaceuticals for somatostatin receptor imaging. Nucl Med Rev Cent East Eur. 2016; 19(2): 126–132.
- Kwekkeboom D, Krenning EP, de Jong M. Peptide receptor imaging and therapy. J Nucl Med. 2000; 41: 1704–1713.
- Kolasińska-Ćwikła A, Łowczak A, Maciejkiewicz KM, et al. Peptide receptor radionuclide therapy for advanced gastroenteropancreatic neuroendocrine tumors — from oncology perspective. Nucl Med Rev Cent East Eur. 2018; 21(2): 115–124.
- Rudisile S, Gosewisch A, Wenter V, et al. Salvage PRRT with Lu-DOTA-octreotate in extensively pretreated patients with metastatic neuroendocrine tumor (NET): dosimetry, toxicity, efficacy, and survival. BMC Cancer. 2019; 19(1): 788.
- Neumann FJ, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2019; 40(2): 87–165.
- Knuuti J, Wijns W, Saraste A, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: The Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC). Eur Heart J. 2020; 41(3): 407–477.
- Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024; 45(36): 3415–3537.
- Baumgartner H, De Backer J, Babu-Narayan SV, et al. 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J. 2021; 42(6): 563–645.
- Halvorsen S, Mehilli J, Cassese S, et al. 2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery. Eur Heart J. 2022; 43(39): 3826–3924.
- Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022; 43(40): 3997–4126.
- Lyon AR, López-Fernández T, Couch LS, et al. 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). Eur Heart J. 2022; 43(41): 4229–4361.
- Teresińska A, Królicki L. Registry of nuclear medicine procedures in cardiology in Poland in 2019–2021. Nucl Med Rev Cent East Eur. 2023; 26: 158–164.
- Werner RA, Thackeray JT, Diekmann J, et al. The changing face of nuclear cardiology: guiding cardiovascular care toward molecular medicine. J Nucl Med. 2020; 61(7): 951–961.
- Bourque JM, Beller GA. Nuclear cardiology: the past, present, and future. Circ Cardiovasc Imaging. 2024; 17(5): e016875.
- Arbelo E, Protonotarios A, Gimeno JR, et al. 2023 ESC Guidelines for the management of cardiomyopathies. Eur Heart J. 2023; 44(37): 3503–3626.
- Gillmore JD, Maurer MS, Falk RH, et al. Nonbiopsy diagnosis of cardiac transthyretin amyloidosis. Circulation. 2016; 133(24): 2404–2412.
- Dorbala S, Kijewski MF. Molecular imaging of systemic and cardiac amyloidosis: recent advances and focus on the future. J Nucl Med. 2023; 64(Suppl 2): 20S–28S.
- Delgado V, Ajmone Marsan N, de Waha S, et al. 2023 ESC Guidelines for the management of endocarditis. Eur Heart J. 2023; 44(39): 3948–4042.
- Bourque JM, Birgersdotter-Green U, Bravo PE, et al. F-FDG PET/CT and radiolabeled leukocyte SPECT/CT imaging for the evaluation of cardiovascular infection in the multimodality context: ASNC imaging indications (ASNC I) series expert consensus recommendations from ASNC, AATS, ACC, AHA, ASE, EANM, HRS, IDSA, SCCT, SNMMI, and STS. JACC Cardiovasc Imaging. 2024; 17(6): 669–701.
- Besson FL, Parienti JJ, Bienvenu B, et al. Diagnostic performance of ¹⁸F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a systematic review and meta-analysis. Eur J Nucl Med Mol Imaging. 2011; 38(9): 1764–1772.
- Barra L, Kanji T, Malette J, et al. CanVasc. Imaging modalities for the diagnosis and disease activity assessment of Takayasu's arteritis: a systematic review and meta-analysis. Autoimmun Rev. 2018; 17(2): 175–187.
- Dejaco C, Ramiro S, Bond M, et al. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice: 2023 update. Ann Rheum Dis. 2024; 83(6): 741–751.
- Lauri C, Signore A, Glaudemans AW, et al. Evidence-based guideline of the European Association of Nuclear Medicine (EANM) on imaging infection in vascular grafts. Eur J Nucl Med Mol Imaging. 2022; 49(10): 3430–3451.
- Reinders Folmer EI, Von Meijenfeldt GCI, Van der Laan MJ, et al. Diagnostic imaging in vascular graft infection: a systematic review and meta-analysis. Eur J Vasc Endovasc Surg. 2018; 56(5): 719–729.
- Puges M, Bérard X, Ruiz JB, et al. Retrospective study comparing WBC scan and F-FDG PET/CT in patients with suspected prosthetic vascular graft infection. Eur J Vasc Endovasc Surg. 2019; 57(6): 876–884.
- Joshi NV, Vesey AT, Williams MC, et al. 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial. Lancet. 2014; 383(9918): 705–713.
- Kwiecinski J, Dey D, Cadet S, et al. Predictors of 18F-sodium fluoride uptake in patients with stable coronary artery disease and adverse plaque features on computed tomography angiography. Eur Heart J Cardiovasc Imaging. 2020; 21(1): 58–66.
- Kwiecinski J, Tzolos E, Adamson PD, et al. Coronary f-sodium fluoride uptake predicts outcomes in patients with coronary artery disease. J Am Coll Cardiol. 2020; 75(24): 3061–3074.
- Kwiecinski J, Tzolos E, Meah MN, et al. Machine learning with f-sodium fluoride PET and quantitative plaque analysis on CT angiography for the future risk of myocardial infarction. J Nucl Med. 2022; 63(1): 158–165.
- Fletcher AJ, Tew YY, Tzolos E, et al. Thoracic aortic f-sodium fluoride activity and ischemic stroke in patients with established cardiovascular disease. JACC Cardiovasc Imaging. 2022; 15(7): 1274–1288.
- Hyafil F, Gimelli A, Slart RH, et al. EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras. Eur J Hybrid Imaging. 2019; 3(1): 11.
- Wells RG, Small GR, Ruddy TD. Myocardial blood flow quantification with SPECT. J Med Imaging Radiat Sci. 2024; 55(2S): S51–S58.
- Fahey FH, Grant FD, Thrall JH. Saul Hertz, MD, and the birth of radionuclide therapy. EJNMMI Phys. 2017; 4(1): 15.
- Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016; 26(1): 1–133.
- Jarząb B, Dedecjus M, Lewiński A, et al. Diagnosis and treatment of thyroid cancer in adult patients — recommendations of Polish Scientific Societies and the National Oncological Strategy. 2022 Update. Endokrynol Pol. 2022; 73(2): 173–300.
- Kwekkeboom DJ, de Herder WW, Kam BL, et al. Treatment with the radiolabeled somatostatin analog [177 Lu-DOTA 0,Tyr3]octreotate: toxicity, efficacy, and survival. J Clin Oncol. 2008; 26(13): 2124–2130.
- Strosberg JR, Srirajaskanthan R, El-Haddad G, et al. Phase 3 trial of lu-Dotatate for midgut neuroendocrine tumors. N Engl J Med. 2017; 376(2): 125–135.
- Morris MJ, Sartor O, de Bono JS, et al. Lutetium-177-PSMA-617 for metastatic castration-resistant prostate cancer. N Engl J Med. 2021; 385(12): 1091–1103.
- Hoskin P, Sartor O, O'Sullivan JM, et al. Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial. Lancet Oncol. 2014; 15(12): 1397–1406.
- Andersson M, Johansson L, Minarik D, et al. Effective dose to adult patients from 338 radiopharmaceuticals estimated using ICRP biokinetic data, ICRP/ICRU computational reference phantoms and ICRP 2007 tissue weighting factors. EJNMMI Phys. 2014; 1(1): 9.
- Cremonesi M, Ferrari M, Bodei L, et al. Dosimetry in peptide radionuclide receptor therapy: a review. J Nucl Med. 2006; 47(9): 1467–1475.
- Taprogge J, Wadsley J, Miles E, et al. Recommendations for multicentre clinical trials involving dosimetry for molecular radiotherapy. Clin Oncol (R Coll Radiol). 2021; 33(2): 131–136.
- Sundlöv A, Sjögreen-Gleisner K, Svensson J, et al. Individualised Lu-DOTATATE treatment of neuroendocrine tumours based on kidney dosimetry. Eur J Nucl Med Mol Imaging. 2017; 44(9): 1480–1489.
- Wadsley J, Flux G. Molecular radiotherapy comes of age. Clin Oncol (R Coll Radiol). 2021; 33(2): 65–67.
- Haug AR. PRRT of neuroendocrine tumors: individualized dosimetry or fixed dose scheme? EJNMMI Res. 2020; 10(1): 35.
- Konijnenberg M, Herrmann K, Kobe C, et al. EANM position paper on article 56 of the Council Directive 2013/59/Euratom (basic safety standards) for nuclear medicine therapy. Eur J Nucl Med Mol Imaging. 2021; 48(1): 67–72.
- ICRU Report 96. Dosimetry-Guided Radiopharmaceutical Therapy, 2021.