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Tumour cell migration and invasion: an impact of cell plasticity and extracellular matrix on metastasis
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Abstract
Migratory and invasive potential of the cell is determined by the type of a tissue from which the cell derives. However, in case of neoplastic cells they display some plasticity of a phenotype which enables changes in the mode of migration. These transitions may influence the metastatic potential of the tumour. Processes described vitally depend on the tumour microenvironment and may be regulated by the dynamic of the extracellular matrix alterations.
Abstract
Migratory and invasive potential of the cell is determined by the type of a tissue from which the cell derives. However, in case of neoplastic cells they display some plasticity of a phenotype which enables changes in the mode of migration. These transitions may influence the metastatic potential of the tumour. Processes described vitally depend on the tumour microenvironment and may be regulated by the dynamic of the extracellular matrix alterations.
About this articleTitle
Tumour cell migration and invasion: an impact of cell plasticity and extracellular matrix on metastasis
Journal
Nowotwory. Journal of Oncology
Issue
Article type
Review paper
Pages
45-52
Published online
2016-04-07
Page views
1277
Article views/downloads
13395
DOI
Bibliographic record
Nowotwory. Journal of Oncology 2016;66(1):45-52.
Authors
Anna Balcerak
Maciej Wakuła
Alicja Trębińska
Ewa A. Grzybowska