A 61-year-old female patient presented with a painless lump located in the right breast. In 2015 she was diagnosed with mammary-type myofibroblastoma (MFB) in the right breast and underwent a resection. In 2016 there was a unilateral relapse and the second tumorectomy was performed. The patient underwent core needle biopsy, which indicated a non-epithelial spindle cell lesion with immunohistochemistry results CD34+;S100–; p63–; CKPAN–; ER–. On the MRI there was a lobular tumour (37 x 42 x 57 mm) with 2 satellite lesions. Due to the size of the tumour and previous breast surgeries, a nipple sparing mastectomy with reconstruction was performed. Histopathology confirmed MFB (fig. 1, fig. 2). MFB is a rare benign spindle cell tumour of the breast. Due to its rare incidence, no risk factors or genetic predispositions are identified . As MFB is well encapsulated, the treatment of choice is surgery without further adjuvant therapy. Only one relapse of MFB has been reported in the literature so far . There is little data concerning recurrence of MFB , therefore careful observation and documentation of recurrent MFBs could prove beneficial in studying the nature of MFB and treating patients.
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NOWOTWORY Journal of Oncology
2023, volume 73, number 5, 323
© Polskie Towarzystwo Onkologiczne
ISSN 0029–540X, e-ISSN: 2300-2115
Rare case of recurrent myofibroblastoma in a female patient
How to cite:
Ciechanowicz S, Kupidłowski P, Wichtowski M. Rare case of recurrent myofibroblastoma in a female patient. NOWOTWORY J Oncol 2023; 73: 323.
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