open access

Vol 67, No 3 (2017)
Research paper (original)
Published online: 2017-12-12
Get Citation

An effectiveness evaluation of the palmar fascia irradiation of patients suffering from Dupuytren’s disease

Tomasz Latusek, Leszek Miszczyk, Grzegorz Gierlach, Piotr Zając
DOI: 10.5603/NJO.2017.0027
·
Nowotwory. Journal of Oncology 2017;67(3):162-167.

open access

Vol 67, No 3 (2017)
Original article
Published online: 2017-12-12

Abstract

Introduction. Dupuytren’s disease (DD) is a fibroproliferative disorder of an unknown etiology manifested by a progressive contracture of fingers. The basic method of the treatment is surgery. Among non-surgical treatments, radiotherapy (RT) represents a relevant method. The aim of the study was to evaluate the efficacy of palmar fascia irradiation in patients with Dupuytren’s Disease.

Material and methods. The research included a group of 117 patients with Dupuytren’s disease irradiated in the Department of Radiotherapy in the Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology in Gliwice. Patients’ medical records from the Institute of Oncology in Gliwice and the Provincial Hospital of Orthopedics and Trauma Surgery in Piekary Śląskie have been analysed retrospectively. The following were assessed: smoking history and the subjective evaluation of the effect of the therapy and its side effects before irradiation and check-up visits. All patients were irradiated to a total dose of 21 Gy given in 7 fractions.

Results. After the RT, 35% of patients showed an improvement, in 58% of patients the disease progress stopped, whereas 7% of patients reported a deterioration. During the observation period, 7.5% of patients noted a deterioration of the contracture or the topical condition, in 35% stagnancy was observed, and 57.5% of patients showed a reduction of the contracture and an improvement in the topical condition. After the RT, 87.5% of patients had no side effects, in 7.5% there was a slight skin erythema, 2.5% had superficial epidermis exfoliation, and 2.5% reported dry skin.

Conclusions. The obtained results allow one to conclude that palmar fascia irradiation is an effective method of treatment for patients with Dupuytren’s disease and it is characterised by a low proportion of complications.

Abstract

Introduction. Dupuytren’s disease (DD) is a fibroproliferative disorder of an unknown etiology manifested by a progressive contracture of fingers. The basic method of the treatment is surgery. Among non-surgical treatments, radiotherapy (RT) represents a relevant method. The aim of the study was to evaluate the efficacy of palmar fascia irradiation in patients with Dupuytren’s Disease.

Material and methods. The research included a group of 117 patients with Dupuytren’s disease irradiated in the Department of Radiotherapy in the Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology in Gliwice. Patients’ medical records from the Institute of Oncology in Gliwice and the Provincial Hospital of Orthopedics and Trauma Surgery in Piekary Śląskie have been analysed retrospectively. The following were assessed: smoking history and the subjective evaluation of the effect of the therapy and its side effects before irradiation and check-up visits. All patients were irradiated to a total dose of 21 Gy given in 7 fractions.

Results. After the RT, 35% of patients showed an improvement, in 58% of patients the disease progress stopped, whereas 7% of patients reported a deterioration. During the observation period, 7.5% of patients noted a deterioration of the contracture or the topical condition, in 35% stagnancy was observed, and 57.5% of patients showed a reduction of the contracture and an improvement in the topical condition. After the RT, 87.5% of patients had no side effects, in 7.5% there was a slight skin erythema, 2.5% had superficial epidermis exfoliation, and 2.5% reported dry skin.

Conclusions. The obtained results allow one to conclude that palmar fascia irradiation is an effective method of treatment for patients with Dupuytren’s disease and it is characterised by a low proportion of complications.

Get Citation

Keywords

Dupuytren’s Disease, radiotherapy, Dupuytren’s Contracture

About this article
Title

An effectiveness evaluation of the palmar fascia irradiation of patients suffering from Dupuytren’s disease

Journal

Nowotwory. Journal of Oncology

Issue

Vol 67, No 3 (2017)

Article type

Research paper (original)

Pages

162-167

Published online

2017-12-12

DOI

10.5603/NJO.2017.0027

Bibliographic record

Nowotwory. Journal of Oncology 2017;67(3):162-167.

Keywords

Dupuytren’s Disease
radiotherapy
Dupuytren’s Contracture

Authors

Tomasz Latusek
Leszek Miszczyk
Grzegorz Gierlach
Piotr Zając

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest VM Media sp. z o.o. VM Group sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl