open access

Vol 63, No 2 (2013)
Review paper
Published online: 2013-06-10
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Accelerated Partial Breast Irradiation in the treatment of breast cancer — current status and treatment methods

Janusz Skowronek, Kinga Ambrochowicz, Magdalena Wawrzyniak-Hojczyk, Witold Kycler, Piotr Łaski, Grzegorz Zwierzchowski, Grzegorz Bielęda
Nowotwory. Journal of Oncology 2013;63(2):132-143.

open access

Vol 63, No 2 (2013)
Review article
Published online: 2013-06-10

Abstract

Breast conserving surgery (BCS) with following radiotherapy (EBRT) of the conserved breast became widely accepted
in the last decades for the treatment of early invasive breast cancer. The standard technique of EBRT after BCS is to
treat the whole breast up to a total dose of 45 Gy to 50 Gy. Additional dose is given to the treated volume after EBRT
to boost a portion of the breast to a higher dose. However, over the past 10 years, the application of radiotherapy in
breast cancer has changed. In early stage breast cancer, research has shown that the area requiring radiation treatment
to prevent the cancer from local recurrence is the breast tissue that surrounds the area where the initial cancer
was removed. Because this typically includes only a part of the breast, APBI is now used to treat the targeted portion
of the breast and as a result allows accelerated delivery of the radiation dose in four to fi ve days. Published results
of APBI techniques are very promising. In this article the current status, indications, technical aspects and recently
published results of APBI in breast cancer treatment are presented.

Abstract

Breast conserving surgery (BCS) with following radiotherapy (EBRT) of the conserved breast became widely accepted
in the last decades for the treatment of early invasive breast cancer. The standard technique of EBRT after BCS is to
treat the whole breast up to a total dose of 45 Gy to 50 Gy. Additional dose is given to the treated volume after EBRT
to boost a portion of the breast to a higher dose. However, over the past 10 years, the application of radiotherapy in
breast cancer has changed. In early stage breast cancer, research has shown that the area requiring radiation treatment
to prevent the cancer from local recurrence is the breast tissue that surrounds the area where the initial cancer
was removed. Because this typically includes only a part of the breast, APBI is now used to treat the targeted portion
of the breast and as a result allows accelerated delivery of the radiation dose in four to fi ve days. Published results
of APBI techniques are very promising. In this article the current status, indications, technical aspects and recently
published results of APBI in breast cancer treatment are presented.
Get Citation
About this article
Title

Accelerated Partial Breast Irradiation in the treatment of breast cancer — current status and treatment methods

Journal

Nowotwory. Journal of Oncology

Issue

Vol 63, No 2 (2013)

Article type

Review paper

Pages

132-143

Published online

2013-06-10

Page views

1225

Article views/downloads

5493

Bibliographic record

Nowotwory. Journal of Oncology 2013;63(2):132-143.

Authors

Janusz Skowronek
Kinga Ambrochowicz
Magdalena Wawrzyniak-Hojczyk
Witold Kycler
Piotr Łaski
Grzegorz Zwierzchowski
Grzegorz Bielęda

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