Vol 55, No 1 (2021)
Research Paper
Published online: 2020-11-26
Submitted: 2020-08-03
Accepted: 2020-09-25
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Predictors of outcome events and 6-year mortality after carotid endarterectomy and carotid stenting in patients with carotid artery stenosis

Norbert Leško, Milan Maretta, Matej Škorvánek, Mária Frankovičová, Vladimír Sihotský, Ľubomír Špak, Zuzana Gdovinová
DOI: 10.5603/PJNNS.a2020.0089
·
Pubmed: 33242214
·
Neurol Neurochir Pol 2021;55(1):67-73.

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Vol 55, No 1 (2021)
Research papers
Published online: 2020-11-26
Submitted: 2020-08-03
Accepted: 2020-09-25

Abstract

Aim. The aim of our study was to evaluate the results of CEA and CAS in patients with carotid artery stenosis, and their effect on long-term mortality and morbidity, as well as to identify predictors of long-term mortality in a single-centre observational study.

Clinical rationale. While data on short-term morbidity and mortality after carotid endarterectomy (CEA) and carotid stenting (CAS) is robust, there is only a limited amount of literature on long-term mortality and its predictors five years-plus post these procedures.

Material and methods. Consecutive patients with symptomatic and asymptomatic internal carotid artery stenosis treated with CEA or CAS in a single centre in eastern Slovakia between 2012 and 2014 were included. We recorded basic sociodemographic data, the presence of co-morbidities and periprocedural complications. Clinical and sonographic follow-up was performed three and 12 months after the procedures. Patient survival data and any stroke data was obtained at the end of a six-year follow-up.

Results. We included 259 patients after CEA (mean age 67.4 ± 8.5, 64.5% men) and 321 after CAS (mean age 66.9 ± 8.4, 73.5% men). We did not identify a statistically significant difference in short-term or long-term mortality, survival times, or the presence of short-term or long-term complications between the CEA and CAS groups. Predictors of long-term mortality included age and diabetes mellitus in both cohorts. Repeated interventions were related to increased mortality only in the CAS cohort. Conclusions. The results of our study show that long-term mortality does not differ between CEA and CAS.

Abstract

Aim. The aim of our study was to evaluate the results of CEA and CAS in patients with carotid artery stenosis, and their effect on long-term mortality and morbidity, as well as to identify predictors of long-term mortality in a single-centre observational study.

Clinical rationale. While data on short-term morbidity and mortality after carotid endarterectomy (CEA) and carotid stenting (CAS) is robust, there is only a limited amount of literature on long-term mortality and its predictors five years-plus post these procedures.

Material and methods. Consecutive patients with symptomatic and asymptomatic internal carotid artery stenosis treated with CEA or CAS in a single centre in eastern Slovakia between 2012 and 2014 were included. We recorded basic sociodemographic data, the presence of co-morbidities and periprocedural complications. Clinical and sonographic follow-up was performed three and 12 months after the procedures. Patient survival data and any stroke data was obtained at the end of a six-year follow-up.

Results. We included 259 patients after CEA (mean age 67.4 ± 8.5, 64.5% men) and 321 after CAS (mean age 66.9 ± 8.4, 73.5% men). We did not identify a statistically significant difference in short-term or long-term mortality, survival times, or the presence of short-term or long-term complications between the CEA and CAS groups. Predictors of long-term mortality included age and diabetes mellitus in both cohorts. Repeated interventions were related to increased mortality only in the CAS cohort. Conclusions. The results of our study show that long-term mortality does not differ between CEA and CAS.

Get Citation

Keywords

carotid stenting, carotid endarterectomy, mortality, predictors

About this article
Title

Predictors of outcome events and 6-year mortality after carotid endarterectomy and carotid stenting in patients with carotid artery stenosis

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 55, No 1 (2021)

Article type

Research Paper

Pages

67-73

Published online

2020-11-26

DOI

10.5603/PJNNS.a2020.0089

Pubmed

33242214

Bibliographic record

Neurol Neurochir Pol 2021;55(1):67-73.

Keywords

carotid stenting
carotid endarterectomy
mortality
predictors

Authors

Norbert Leško
Milan Maretta
Matej Škorvánek
Mária Frankovičová
Vladimír Sihotský
Ľubomír Špak
Zuzana Gdovinová

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