open access

Vol 52, No 6 (2018)
Review articles
Submitted: 2019-11-05
Accepted: 2019-11-05
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Benign epilepsy with centrotemporal spikes – Current concepts of diagnosis and treatment

P. Dryżałowski, S. Jóźwiak, M. Franckiewicz, J. Strzelecka
Pubmed: 30219586
·
Neurol Neurochir Pol 2018;52(6):677-689.

open access

Vol 52, No 6 (2018)
Review articles
Submitted: 2019-11-05
Accepted: 2019-11-05

Abstract

Benign epilepsy with centrotemporal spikes (BECTS) is the most common focal epilepsy of
the childhood and also one of the best known. It has a proclivity to start at a particular age and remit spontaneously before adolescence. Majority of patients may avoid long-term treatment, because of the mild course and very good outcome. Only few patients may present cognitive deficits if the proper treatment is not implied. BECTS is a part of heterogeneous group of syndromes that consists of Landau-Kleffner Syndrome (LKS), Continuous Spike-and-Wave during Sleep (CSWS) and Atypical benign partial epilepsy (ABPE). These syndromes may be also a result of various trajectories that BECTS may evolve to. Disease is suggested to have genetic origins, as some patients have relatives with different types of epilepsy. The discovery of the pathogenic mechanism of the disease and implementation of targeted therapy belong to the main challenges in the treatment of these patients.

Abstract

Benign epilepsy with centrotemporal spikes (BECTS) is the most common focal epilepsy of
the childhood and also one of the best known. It has a proclivity to start at a particular age and remit spontaneously before adolescence. Majority of patients may avoid long-term treatment, because of the mild course and very good outcome. Only few patients may present cognitive deficits if the proper treatment is not implied. BECTS is a part of heterogeneous group of syndromes that consists of Landau-Kleffner Syndrome (LKS), Continuous Spike-and-Wave during Sleep (CSWS) and Atypical benign partial epilepsy (ABPE). These syndromes may be also a result of various trajectories that BECTS may evolve to. Disease is suggested to have genetic origins, as some patients have relatives with different types of epilepsy. The discovery of the pathogenic mechanism of the disease and implementation of targeted therapy belong to the main challenges in the treatment of these patients.

Get Citation

Keywords

BECTS, Epilepsy, Genetics, Diagnosis, Treatment

About this article
Title

Benign epilepsy with centrotemporal spikes – Current concepts of diagnosis and treatment

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 6 (2018)

Pages

677-689

Pubmed

30219586

Bibliographic record

Neurol Neurochir Pol 2018;52(6):677-689.

Keywords

BECTS
Epilepsy
Genetics
Diagnosis
Treatment

Authors

P. Dryżałowski
S. Jóźwiak
M. Franckiewicz
J. Strzelecka

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