open access

Vol 52, No 4 (2018)
Case reports
Submitted: 2017-09-17
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Primary Ewing sarcoma of the axis-C2: A case report and the review of the literature

Kyriakos Paraskeva, Dimitrios Giakoumettis, Ioannis Nikas, George Georgoulis, George Sfakianos, Marios S. Themistocleous
DOI: 10.1016/j.pjnns.2018.02.005
·
Neurol Neurochir Pol 2018;52(4):534-542.

open access

Vol 52, No 4 (2018)
Case reports
Submitted: 2017-09-17

Abstract

Introduction

Neck pain and torticollis are common symptoms in the pediatric population that rarely requires further investigation. However, in case symptoms persist, then a more meticulously approach should be considered. Underlying conditions such as infections, neck injury, autoimmune disorders or even cervical spine cancer should be excluded from diagnosis. Cervical spine cancer is a rare neurosurgical entity in the pediatric population and even rarer is atlantoaxial Ewing's sarcoma. In this report, we present a rare case of primary Ewing's sarcoma of the axis.

Case report

A 3.5-year-old female with progressive neck pain and intermittent episodes of torticollis was referred to our outpatient clinic. Imaging studies revealed a malignant tumor located on C2 vertebra. Diagnosis of Ewing's Sarcoma was confirmed via open biopsy and the patient was treated with Euro-EWING 99 chemotherapy.

Conclusion

Pediatric neck pain and/or torticollis should raise high suspicion for malignancy of cervical spine. Modern diagnostic means and techniques can assist in the screening and diagnosis of these tumors.

Abstract

Introduction

Neck pain and torticollis are common symptoms in the pediatric population that rarely requires further investigation. However, in case symptoms persist, then a more meticulously approach should be considered. Underlying conditions such as infections, neck injury, autoimmune disorders or even cervical spine cancer should be excluded from diagnosis. Cervical spine cancer is a rare neurosurgical entity in the pediatric population and even rarer is atlantoaxial Ewing's sarcoma. In this report, we present a rare case of primary Ewing's sarcoma of the axis.

Case report

A 3.5-year-old female with progressive neck pain and intermittent episodes of torticollis was referred to our outpatient clinic. Imaging studies revealed a malignant tumor located on C2 vertebra. Diagnosis of Ewing's Sarcoma was confirmed via open biopsy and the patient was treated with Euro-EWING 99 chemotherapy.

Conclusion

Pediatric neck pain and/or torticollis should raise high suspicion for malignancy of cervical spine. Modern diagnostic means and techniques can assist in the screening and diagnosis of these tumors.

Get Citation

Keywords

BSAP, CD, CT, EWS/FLI, FLi-1, INI-1, MRI, NCAM, PAX-5, PNET, RT-PCR, TdT

About this article
Title

Primary Ewing sarcoma of the axis-C2: A case report and the review of the literature

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 4 (2018)

Pages

534-542

DOI

10.1016/j.pjnns.2018.02.005

Bibliographic record

Neurol Neurochir Pol 2018;52(4):534-542.

Keywords

BSAP
CD
CT
EWS/FLI
FLi-1
INI-1
MRI
NCAM
PAX-5
PNET
RT-PCR
TdT

Authors

Kyriakos Paraskeva
Dimitrios Giakoumettis
Ioannis Nikas
George Georgoulis
George Sfakianos
Marios S. Themistocleous

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