open access

Vol 52, No 2 (2018)
Original research articles
Submitted: 2016-12-29
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Significance of noncompliance when treating patients with epilepsy

Rumyana Kuzmanova, Irina Stefanova, Katerina Stambolieva
DOI: 10.1016/j.pjnns.2017.10.005
·
Neurol Neurochir Pol 2018;52(2):215-221.

open access

Vol 52, No 2 (2018)
Original research articles
Submitted: 2016-12-29

Abstract

Introduction

The absence of patient's cooperation when it comes to his/her treatment (“noncompliance”) is typical to chronic diseases and it is significant problem in medical practice. The term “compliance” means patient's capability of strictly adhering to the recommendations concerning the prescribed treatment. The noncompliance with drug regime is frequent case in patients with epilepsy, it is related to increased risk of epileptic seizures’ occurrence and other undesired consequences, including increased costs in the healthcare area.

Objective

The objective of our research is assessing the interconnection between compliance with the treatment and social-demographic and clinical factors in patients with epilepsy.

Contingent and methods

The research covers 131 consecutively included patients with epilepsy of various social-demographic and clinical characteristics. We have utilized analysis of the medical documentation, anamnesis, study of the somatic and neurological status, self-assessment scales and statistical methods.

Results

We established statistically significant positive correlations between the number of patients with poor compliance and the absence of professional/educational occupation, frequency of epileptic seizures, number of the antiepileptic drugs taken during the present and past treatment, the simultaneous presence of poor control of epileptic seizures and adverse drug events being the reason behind the modification of the previous treatment.

Conclusion

Patient's poor compliance, the great frequency of seizures, the higher number of antiepileptic drugs and the adverse drug reactions have negative impact on the course of the epileptic disease. The improved compliance results in optimizing the antiepileptic treatment, improving patients’ condition and significantly cutting down costs incurred in the healthcare area.

Abstract

Introduction

The absence of patient's cooperation when it comes to his/her treatment (“noncompliance”) is typical to chronic diseases and it is significant problem in medical practice. The term “compliance” means patient's capability of strictly adhering to the recommendations concerning the prescribed treatment. The noncompliance with drug regime is frequent case in patients with epilepsy, it is related to increased risk of epileptic seizures’ occurrence and other undesired consequences, including increased costs in the healthcare area.

Objective

The objective of our research is assessing the interconnection between compliance with the treatment and social-demographic and clinical factors in patients with epilepsy.

Contingent and methods

The research covers 131 consecutively included patients with epilepsy of various social-demographic and clinical characteristics. We have utilized analysis of the medical documentation, anamnesis, study of the somatic and neurological status, self-assessment scales and statistical methods.

Results

We established statistically significant positive correlations between the number of patients with poor compliance and the absence of professional/educational occupation, frequency of epileptic seizures, number of the antiepileptic drugs taken during the present and past treatment, the simultaneous presence of poor control of epileptic seizures and adverse drug events being the reason behind the modification of the previous treatment.

Conclusion

Patient's poor compliance, the great frequency of seizures, the higher number of antiepileptic drugs and the adverse drug reactions have negative impact on the course of the epileptic disease. The improved compliance results in optimizing the antiepileptic treatment, improving patients’ condition and significantly cutting down costs incurred in the healthcare area.

Get Citation

Keywords

Adverse event, Antiepileptic treatment, Compliance, Epileptic seizure

About this article
Title

Significance of noncompliance when treating patients with epilepsy

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 2 (2018)

Pages

215-221

DOI

10.1016/j.pjnns.2017.10.005

Bibliographic record

Neurol Neurochir Pol 2018;52(2):215-221.

Keywords

Adverse event
Antiepileptic treatment
Compliance
Epileptic seizure

Authors

Rumyana Kuzmanova
Irina Stefanova
Katerina Stambolieva

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