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Evaluation of simple blood counts as inflammation markers for brain tumor patients
Affiliations- Abant Izzet Baysal University Hospital, Department of Neurosurgery, Bolu, Türkiye
- Abant Izzet Baysal University Hospital, Department of Radiology, Bolu, Türkiye
- Pamukkale University Hospital, Department of Neurosurgery, Denizli, Türkiye
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Abstract
Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.
MethodsWe recorded white blood cell count, neutrophil count, lymphocyte count, hemoglobin, hematocrit, RDW, platelet count, and MPV of the study group at the time of diagnosis and compared to those of the control subjects.
ResultsThe RDW was significantly elevated in study group compared to that of the control subjects (p=0.001). The MPV was significantly lower in study group than that of the control group (p=0.01).
ConclusionDecreased MPV and increased RDW were both associated with brain tumor. However, prospective studies with larger sample sizes are needed to support the results and expose MPV and RDW variations between metastatic and primary brain tumors.
Abstract
Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.
MethodsWe recorded white blood cell count, neutrophil count, lymphocyte count, hemoglobin, hematocrit, RDW, platelet count, and MPV of the study group at the time of diagnosis and compared to those of the control subjects.
ResultsThe RDW was significantly elevated in study group compared to that of the control subjects (p=0.001). The MPV was significantly lower in study group than that of the control group (p=0.01).
ConclusionDecreased MPV and increased RDW were both associated with brain tumor. However, prospective studies with larger sample sizes are needed to support the results and expose MPV and RDW variations between metastatic and primary brain tumors.
Keywords
Brain tumor, Metastasis, Mean platelet volume, Red cell distribution width, Inflammation
About this articleTitle
Evaluation of simple blood counts as inflammation markers for brain tumor patients
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
231-235
Page views
307
Article views/downloads
1066
DOI
10.1016/j.pjnns.2016.03.002
Bibliographic record
Neurol Neurochir Pol 2016;50(4):231-235.
Keywords
Brain tumor
Metastasis
Mean platelet volume
Red cell distribution width
Inflammation
Authors
Yasar Dagistan
Emine Dagistan
Veli Citisli
