open access

Vol 50, No 4 (2016)
Original research articles
Submitted: 2015-04-30
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Evaluation of simple blood counts as inflammation markers for brain tumor patients

Yasar Dagistan, Emine Dagistan, Veli Citisli
DOI: 10.1016/j.pjnns.2016.03.002
·
Neurol Neurochir Pol 2016;50(4):231-235.

open access

Vol 50, No 4 (2016)
Original research articles
Submitted: 2015-04-30

Abstract

Aims

Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.

Methods

We recorded white blood cell count, neutrophil count, lymphocyte count, hemoglobin, hematocrit, RDW, platelet count, and MPV of the study group at the time of diagnosis and compared to those of the control subjects.

Results

The RDW was significantly elevated in study group compared to that of the control subjects (p=0.001). The MPV was significantly lower in study group than that of the control group (p=0.01).

Conclusion

Decreased MPV and increased RDW were both associated with brain tumor. However, prospective studies with larger sample sizes are needed to support the results and expose MPV and RDW variations between metastatic and primary brain tumors.

Abstract

Aims

Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.

Methods

We recorded white blood cell count, neutrophil count, lymphocyte count, hemoglobin, hematocrit, RDW, platelet count, and MPV of the study group at the time of diagnosis and compared to those of the control subjects.

Results

The RDW was significantly elevated in study group compared to that of the control subjects (p=0.001). The MPV was significantly lower in study group than that of the control group (p=0.01).

Conclusion

Decreased MPV and increased RDW were both associated with brain tumor. However, prospective studies with larger sample sizes are needed to support the results and expose MPV and RDW variations between metastatic and primary brain tumors.

Get Citation

Keywords

Brain tumor, Metastasis, Mean platelet volume, Red cell distribution width, Inflammation

About this article
Title

Evaluation of simple blood counts as inflammation markers for brain tumor patients

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 50, No 4 (2016)

Pages

231-235

DOI

10.1016/j.pjnns.2016.03.002

Bibliographic record

Neurol Neurochir Pol 2016;50(4):231-235.

Keywords

Brain tumor
Metastasis
Mean platelet volume
Red cell distribution width
Inflammation

Authors

Yasar Dagistan
Emine Dagistan
Veli Citisli

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