Vol 50, No 4 (2016)

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Evaluation of simple blood counts as inflammation markers for brain tumor patients

Yasar Dagistan1, Emine Dagistan2, Veli Citisli3
DOI: 10.1016/j.pjnns.2016.03.002
Neurol Neurochir Pol 2016;50(4):231-235.

Abstract

Aims

Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate inflammatory markers in brain tumor patients. We aimed to observe RDW and MPV values of tumor patients and compare to those in healthy population.

Methods

We recorded white blood cell count, neutrophil count, lymphocyte count, hemoglobin, hematocrit, RDW, platelet count, and MPV of the study group at the time of diagnosis and compared to those of the control subjects.

Results

The RDW was significantly elevated in study group compared to that of the control subjects (p=0.001). The MPV was significantly lower in study group than that of the control group (p=0.01).

Conclusion

Decreased MPV and increased RDW were both associated with brain tumor. However, prospective studies with larger sample sizes are needed to support the results and expose MPV and RDW variations between metastatic and primary brain tumors.

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Neurologia i Neurochirurgia Polska